Tenofovir Alafenamide 25 mg (TAF) is an advanced antiviral medication prescribed for the treatment of chronic Hepatitis B virus (HBV) infection and HIV-1 infection. It belongs to the class of nucleotide reverse transcriptase inhibitors (NRTIs), which block viral replication and reduce the viral load in the body. Compared to older formulations such as Tenofovir Disoproxil Fumarate (TDF), TAF offers enhanced kidney safety and better bone health, making it suitable for long-term therapy. This medication is approved for adults and adolescents weighing at least 35 kg, often used as part of combination therapy with other antiviral drugs. Uses of Tenofovir Alafenamide 25 mg Tablet Primary uses include: Chronic Hepatitis B Treatment: Reduces viral load and controls liver inflammation. Prevents progression to liver cirrhosis, liver failure, or hepatocellular carcinoma. Supports overall liver health by targeting the virus inside liver cells. HIV Management (Combination Therapy): Often included in antiretroviral therapy (ART) regimens for adults. Available in fixed-dose combinations with drugs like Emtricitabine (FTC) for simplified treatment. Prevention of Liver Complications: Reduces the risk of liver failure, cirrhosis, and liver cancer in chronic HBV patients. Immune Support: Helps stabilize immune function in individuals with HBV infection. How Tenofovir Alafenamide Works Tenofovir Alafenamide is a prodrug of Tenofovir. After ingestion, it converts into active tenofovir diphosphate inside infected cells. The active compound: Inhibits reverse transcriptase, an enzyme essential for viral replication. Stops the virus from multiplying, lowering the viral load in the blood. Helps the immune system control infection and prevents long-term liver damage. Because TAF is active at lower doses in target cells, it has reduced systemic exposure, making it safer for kidneys and bones compared to TDF. How to Take Tenofovir Alafenamide 25 mg Take one tablet daily, preferably with food to improve absorption. Swallow the tablet whole with water; do not crush or chew. Follow your doctor’s instructions regarding dosage and duration. Do not stop the medication on your own to avoid viral rebound. Benefits of Tenofovir Alafenamide Effective Viral Suppression: Reduces viral load in HBV and HIV, slowing disease progression. Kidney and Bone Safety: Lower systemic exposure compared to older formulations. Long-Term Therapy: Suitable for prolonged use with minimal side effects. Convenient Dosing: Once-daily regimen improves adherence and reduces missed doses. Improved Quality of Life: Controls infection, prevents liver damage, and supports immune function. Side Effects of Tenofovir Alafenamide 25 mg While generally well-tolerated, some users may experience: Nausea Headache Fatigue Abdominal discomfort Dizziness Diarrhea Insomnia Mild weight loss Rash or skin irritation Rare: Elevated liver enzymes Serious side effects are uncommon. Kidney or bone issues are less frequent compared to older Tenofovir formulations. Contact your doctor immediately if unusual symptoms occur. Why Choose Steris Healthcare for Tenofovir Alafenamide 25 mg? High-Quality Manufacturing: Produced under strict quality standards. Enhanced Safety: Reduced risk of kidney and bone toxicity. Once-Daily Dosing: Promotes better adherence and consistent viral suppression. Reliable Partner: Steris Healthcare is committed to patient safety and effective antiviral therapy. Frequently Asked Questions (FAQs) What is Tenofovir Alafenamide 25 mg used for? It is used to treat chronic HBV infection and is sometimes included in HIV combination therapy to reduce viral load and prevent liver damage. What class does it belong to? TAF belongs to nucleotide reverse transcriptase inhibitors (NRTIs). What is Tenofovir Alafenamide? It is an antiviral prodrug that converts into tenofovir diphosphate inside infected cells, offering strong antiviral activity with improved kidney and bone safety. How long should I take Tenofovir for Hepatitis B? Often taken long-term or indefinitely. Do not stop without medical guidance. How long does Tenofovir stay in the body? Its active form remains in cells for several days, allowing once-daily dosing. What vitamins should be avoided with Hepatitis B? Avoid high doses of Vitamin A, Vitamin B3 (niacin), and unnecessary iron supplements, as they may stress the liver. Always consult your doctor.
| Active Ingredient: | Tenofovir Alafenamide 25 Mg |
| Brand Name: | TELAVINCE AF25 |
| Package SIZE | 30 Tablets |
| Manufactured By | Steris Healthcare Pvt Ltd |
| Colour | Titanium Dioxide IP |
| Dosage | As Directed By The Physician |
| Storage | Store In A Cool & Dry Place |
| Country of origin | INDIA |