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Paracetamol Infusion IP – METAPECT 1% W/V

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METAPECT 1% W/V is a sterile Paracetamol Infusion IP formulated for intravenous (IV) administration to provide effective relief from pain and fever, especially in clinical and hospital settings. Paracetamol (also known as acetaminophen) is one of the most widely used analgesic and antipyretic agents worldwide due to its proven efficacy, safety profile, and rapid onset of action.

The infusion form of paracetamol is particularly beneficial for patients who are unable to take oral medications, such as those who are post-operative, critically ill, unconscious, or experiencing severe nausea and vomiting. METAPECT 1% W/V ensures fast and reliable pain and fever control through direct bloodstream delivery, making it an essential medication in emergency rooms, intensive care units, and surgical wards.

With its predictable pharmacological action and minimal gastrointestinal irritation, METAPECT 1% W/V plays a vital role in modern pain management protocols and fever control strategies.

Uses

METAPECT 1% W/V is used in a variety of medical and surgical situations, including:

  • Management of Mild to Moderate Pain: Effective for post-operative pain, musculoskeletal pain, and procedural discomfort.

  • Adjunct in Severe Pain Management: Used alongside opioids or other analgesics to enhance pain relief and reduce opioid requirements.

  • Reduction of Fever (Pyrexia): Helps lower high body temperature caused by infections, inflammatory conditions, or post-surgical responses.

  • Post-Surgical Care: Commonly administered after surgeries when oral intake is restricted.

  • Critical Care Settings: Suitable for patients in ICU or emergency care who require rapid pain or fever control.

  • Patients Unable to Take Oral Medication: Ideal for patients with vomiting, swallowing difficulties, or gastrointestinal disorders.

METAPECT 1% W/V is widely trusted in hospitals for its rapid, consistent, and effective therapeutic action.

Benefits

METAPECT 1% W/V offers several clinical and practical benefits:

  • Rapid Onset of Action: Intravenous administration ensures quick relief from pain and fever.

  • Effective Pain Control: Relieves mild to moderate pain and supports multimodal analgesia strategies.

  • Excellent Antipyretic Effect: Quickly reduces elevated body temperature

  • Gentle on the Stomach: Unlike some oral analgesics, IV paracetamol does not cause gastric irritation.

  • Opioid-Sparing Effect: Reduces the need for higher doses of opioids, lowering the risk of opioid-related side effects.

  • Predictable Pharmacokinetics: Provides consistent plasma concentrations for reliable symptom control.

  • Safe for Wide Patient Groups: When used appropriately, it is suitable for adults, elderly patients, and certain pediatric cases under medical supervision.

  • Essential in Hospital Protocols: Widely included in post-operative and critical care pain management guidelines.

These benefits make METAPECT 1% W/V a cornerstone medication in acute pain and fever management.

Dosage

The dosage of METAPECT 1% W/V must be determined and administered by qualified healthcare professionals only. General dosage guidelines include:

  • Adults and Adolescents (≥50 kg):
    Typically, 1 g (100 ml of 1% solution) administered intravenously every 4–6 hours, not exceeding the maximum daily dose as recommended by clinical guidelines.

  • Patients Weighing <50 kg:
    Dose is calculated based on body weight and clinical condition, under strict medical supervision.

  • Administration Method:
    The infusion is administered intravenously over a specified period, usually around 15 minutes

  • Dose Adjustments:
    Required in patients with liver impairment, chronic alcoholism, malnutrition, or dehydration.

  • Duration of Therapy:
    Short-term use is preferred unless otherwise directed by a physician.

Strict adherence to prescribed dosage is essential to prevent toxicity and ensure patient safety.

Side Effects

METAPECT 1% W/V is generally well tolerated when administered correctly. However, some patients may experience side effects:

Common Side Effects

  • Mild pain or burning sensation at the injection site

  • Nausea

  • Headache

  • Mild drop in blood pressure during infusion

Rare but Serious Side Effects

  • Allergic reactions such as rash, itching, or swelling

  • Liver enzyme elevation with prolonged or excessive dosing

  • Severe hypersensitivity reactions (very rare)

Most side effects are mild and transient. Any unexpected or severe reactions should be reported immediately to a healthcare professional. Regular monitoring helps ensure safe use, especially in high-risk patients.

Precautions and Warning

Before administering METAPECT 1% W/V, the following precautions should be considered:

  • Liver Disease: Use with caution in patients with liver impairment, hepatitis, or chronic alcohol use.

  • Maximum Dose Limits: Do not exceed the recommended daily dose to avoid liver toxicity.

  • Drug Interactions: Inform healthcare providers about all medications being taken, especially other paracetamol-containing products.

  • Pregnancy and Breastfeeding: Should be used only when clearly needed and under medical supervision.

  • Renal Impairment: Dose adjustment may be required in patients with kidney dysfunction.

  • Not for Self-Administration: This infusion must be administered by trained medical personnel in a clinical setting.

Following these precautions ensures safe, effective, and responsible use of METAPECT 1% W/V.

Conclusion

paracetamol infusion ip

METAPECT 1% W/V (Paracetamol Infusion IP) is a reliable, fast-acting, and widely trusted solution for the management of pain and fever in hospital and clinical settings. Its intravenous formulation ensures rapid therapeutic action, making it especially valuable for patients who cannot take oral medications or require immediate symptom relief.

With a well-established safety profile, excellent tolerability, and proven effectiveness, METAPECT 1% W/V plays a crucial role in post-operative care, emergency medicine, and critical care environments. When used responsibly under professional supervision, it contributes significantly to patient comfort, recovery, and overall clinical outcomes.


 2025-12-20T12:11:29