Etoricoxib and Paracetamol Tablet STERISCOX PCM 60 is a powerful combination medication formulated by Steris Healthcare to provide effective relief from pain and inflammation. It combines two well-established ingredients: Etoricoxib 60 mg, a selective COX-2 inhibitor, and Paracetamol 325 mg, a commonly used analgesic and antipyretic. Together, they work synergistically to reduce pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. This dual-action formulation ensures quicker and sustained relief, making it suitable for patients suffering from chronic musculoskeletal disorders, joint stiffness, or flare-ups of inflammatory arthritis. What is STERISCOX PCM 60? STERISCOX PCM 60 is a fixed-dose combination tablet that contains: Etoricoxib 60 mg – a selective COX-2 enzyme inhibitor that helps reduce inflammation and pain while minimizing gastric side effects often caused by non-selective NSAIDs. Paracetamol 325 mg – a widely trusted pain reliever and fever reducer that enhances the analgesic effect of Etoricoxib without adding much gastrointestinal burden. This formulation is particularly beneficial for individuals who need long-term anti-inflammatory therapy with added pain control. Uses of STERISCOX PCM 60 STERISCOX PCM 60 is used for the management of a variety of painful and inflammatory conditions, including: Rheumatoid Arthritis Ankylosing Spondylitis Osteoarthritis Muscle and joint pain Low back pain Dental pain Postoperative pain This medicine is designed to provide consistent pain relief, improve joint mobility, and help patients maintain an active lifestyle. Mechanism of Action Etoricoxib selectively inhibits cyclooxygenase-2 (COX-2), an enzyme responsible for pain and inflammation. By blocking COX-2, it minimizes swelling and discomfort without irritating the stomach lining. Paracetamol works by blocking pain signals in the brain and lowering body temperature, complementing the action of Etoricoxib for faster relief. Dosage and Administration The usual recommended dose is one tablet once daily or as directed by a healthcare professional. It is best taken after food to minimize the risk of gastric discomfort. Do not exceed the prescribed dosage or duration. Side Effects of STERISCOX PCM 60 While generally well-tolerated, some patients may experience side effects such as: Stomach pain or indigestion Nausea or vomiting Dizziness or headache Fatigue or drowsiness Raised blood pressure (with long-term use of Etoricoxib) Rarely, liver enzyme elevations or allergic reactions If any side effects persist or worsen, consult your doctor promptly. Precautions Before Using STERISCOX PCM 60 Avoid using in patients with known allergy to NSAIDs or paracetamol. Not recommended for individuals with active peptic ulcer disease or gastrointestinal bleeding. Caution is advised in patients with hypertension, cardiovascular disease, liver or kidney impairment. Do not consume alcohol while on this medication, as it may increase the risk of liver damage. Not recommended during pregnancy or breastfeeding unless clearly advised by a physician. Regular monitoring may be required for long-term users, especially for liver and kidney function. Drug Interactions: What Drugs Interact with STERISCOX PCM 60? Certain medications can interact with STERISCOX PCM 60 and may require dosage adjustments or monitoring: Warfarin or other anticoagulants – increased risk of bleeding Methotrexate – may raise methotrexate levels in the body Lithium – may increase lithium concentration Diuretics and ACE inhibitors – may reduce kidney function Other NSAIDs or corticosteroids – increased risk of GI side effects Alcohol and hepatotoxic drugs – increase liver damage risk with paracetamol Always inform your healthcare provider about all the medications you are taking, including over-the-counter drugs and supplements. Conclusion STERISCOX PCM 60 is a reliable and effective solution for managing moderate to severe pain associated with arthritis and other inflammatory conditions. The unique combination of Etoricoxib 60 mg and Paracetamol 325 mg offers superior pain control with a reduced risk of gastrointestinal complications. It is an ideal choice for patients needing sustained anti-inflammatory support and analgesic coverage, backed by Steris Healthcare’s commitment to quality and patient well-being.