Gliclazide SR 60 mg GLICLAGALZE MR 60 is an oral anti-diabetic medication containing Gliclazide SR (Sustained Release) 60 mg. It belongs to the class of medicines known as sulfonylureas, which are used to control Type 2 Diabetes Mellitus. This medicine works by stimulating the pancreas to produce more insulin, thereby reducing elevated blood glucose levels. The sustained release (SR) formulation ensures a steady and prolonged effect throughout the day, minimizing fluctuations in blood sugar levels. GLICLAGALZE MR 60 is generally prescribed when diet, exercise, and lifestyle modifications alone are not sufficient to achieve adequate glycemic control. It may also be used in combination with other anti-diabetic medications like metformin, DPP-4 inhibitors, or insulin if needed. Uses of GLICLAGALZE MR 60 This medicine is primarily used for: Management of Type 2 Diabetes Mellitus (T2DM) Improving blood sugar control when diet and exercise are not enough Reducing the risk of diabetic complications such as neuropathy, nephropathy, retinopathy, and cardiovascular issues Long-term glucose regulation due to its sustained release formulation, ensuring once-daily convenience Side Effects of GLICLAGALZE MR 60 Like all medications, GLICLAGALZE MR 60 may cause side effects. Most are mild and manageable, but some require medical attention: Common side effects: Hypoglycemia (low blood sugar – dizziness, sweating, shakiness, hunger) Headache Nausea or stomach discomfort Weight gain (in some patients) Less common but possible side effects: Skin reactions like rash or itching Liver function abnormalities (rare) Visual disturbances (temporary, due to changes in blood sugar) Hematological issues such as reduced white blood cells or platelets (rare) If severe hypoglycemia, jaundice, or unusual fatigue occurs, patients should consult their doctor immediately. Precautions Before Using GLICLAGALZE MR 60 Patients should follow certain precautions before starting this medication: Medical conditions: Avoid if you have Type 1 diabetes, diabetic ketoacidosis, or severe kidney/liver impairment. Hypoglycemia risk: Take meals regularly and avoid skipping them, as this drug increases insulin secretion. Pregnancy & breastfeeding: Use only if prescribed by a doctor, as safety in these cases is not fully established. Elderly patients: Require close monitoring, as they are more prone to hypoglycemia. Alcohol consumption: Should be limited or avoided, as it increases the risk of hypoglycemia. Surgery or illness: Inform your doctor if you are undergoing surgery, experiencing severe infection, or trauma, as temporary insulin therapy may be needed. Drug Interactions GLICLAGALZE MR 60 may interact with other medicines, which can either increase or decrease its effectiveness: Drugs that increase hypoglycemia risk: Insulin, other sulfonylureas, metformin, DPP-4 inhibitors, GLP-1 agonists, certain antibiotics (e.g., sulfonamides), and antifungals. Drugs that reduce effectiveness: Corticosteroids, oral contraceptives, diuretics, and thyroid hormones. Beta-blockers: Can mask symptoms of hypoglycemia such as rapid heartbeat. Alcohol: Enhances the risk of low blood sugar and should be avoided. Always inform your doctor about all ongoing medications before starting GLICLAGALZE MR 60. Conclusion GLICLAGALZE MR 60 (Gliclazide SR 60 mg) is a reliable and effective treatment option for managing Type 2 Diabetes Mellitus, particularly for patients who require steady, all-day blood sugar control. Its sustained-release formulation makes it convenient with once-daily dosing, ensuring smoother glucose regulation and reducing the risk of fluctuations. When combined with a healthy diet, regular exercise, and lifestyle modifications, this medication helps patients maintain better long-term glycemic control and reduces the risk of serious diabetes-related complications.