METROTREX 10

Description

Methotrexate 10mg METROTREX 10 is a prescription medication formulated with Methotrexate, a powerful disease-modifying antirheumatic drug (DMARD) widely used for the treatment of autoimmune disorders and certain types of cancer. It is highly effective in controlling inflammatory and proliferative conditions by interfering with the growth of abnormal cells and modulating the immune system’s response. Methotrexate 10mg is commonly prescribed for chronic conditions such as rheumatoid arthritis, psoriasis, psoriatic arthritis, and certain malignancies, including leukemia, lymphoma, and osteosarcoma. By regulating abnormal cell proliferation and immune responses, METROTREX 10 helps reduce pain, inflammation, joint damage, and disease progression, significantly improving patient quality of life. Composition and Mechanism of Action Active Ingredient: Methotrexate 10mg Mechanism of Action: Methotrexate is a folate antagonist, which inhibits the enzyme dihydrofolate reductase (DHFR). By blocking DHFR, it prevents the synthesis of DNA, RNA, and proteins necessary for the rapid division of abnormal or immune cells. In autoimmune conditions like rheumatoid arthritis, Methotrexate reduces immune system hyperactivity, thereby decreasing inflammation and joint damage. In oncology, it prevents the multiplication of cancerous cells, slowing disease progression. This dual functionality makes METROTREX 10 an essential medication for managing both autoimmune diseases and certain cancers. Key Benefits Effective Autoimmune Management: Controls symptoms of rheumatoid arthritis, psoriatic arthritis, and severe psoriasis. Reduces Inflammation and Pain: Helps relieve joint swelling, stiffness, and discomfort. Slows Disease Progression: Protects joints from long-term damage and deformities in chronic autoimmune disorders. Cancer Therapy: Assists in the treatment of certain cancers by inhibiting abnormal cell growth. Convenient Dosage: Oral tablets ensure ease of administration and compliance. Indications METROTREX 10 is prescribed for: Rheumatoid arthritis and juvenile idiopathic arthritis Psoriatic arthritis and severe psoriasis Certain types of cancers, including: Acute lymphoblastic leukemia (ALL) Non-Hodgkin lymphoma Osteosarcoma and other malignancies as per oncologist guidance Other inflammatory autoimmune disorders as determined by a physician Dosage and Administration Dosage: Varies according to the condition being treated and patient-specific factors. For autoimmune disorders: Typically once weekly, as prescribed by a physician. For cancer therapy: Dosage depends on disease type, stage, and patient weight. Administration: Take orally with water, preferably after food to reduce gastrointestinal discomfort. Important: Do not exceed the prescribed dose. Methotrexate overdose can cause severe toxicity. Note: Regular blood tests and liver/kidney function monitoring are essential during treatment. Safety Information Contraindications: Known hypersensitivity to Methotrexate Pregnant or breastfeeding women (high risk of fetal harm) Severe liver, kidney, or bone marrow disorders Precautions: Regular monitoring of blood counts, liver function, and kidney function is mandatory. Avoid alcohol, as it increases the risk of liver toxicity. Report any signs of infection, unexplained bruising, or bleeding immediately. Use effective contraception during and after therapy. Side Effects: Common side effects may include: Nausea, vomiting, or loss of appetite Mouth ulcers or oral irritation Fatigue or dizziness Mild hair thinning Severe side effects are rare but may include liver damage, lung inflammation, or bone marrow suppression. Immediate medical attention is required in such cases. Why Choose METROTREX 10 METROTREX 10 is a trusted solution for patients requiring disease-modifying therapy for autoimmune disorders or cancer. Its scientifically proven efficacy, combined with precise dosing and oral convenience, makes it a reliable choice for healthcare providers and patients alike. Regular use under professional supervision can control symptoms, slow disease progression, and improve overall quality of life.