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nitrofurantoin sustained release tablets Urinary T...

nitrofurantoin sustained release tablets

Urinary Tract Infections (UTIs) are among the most common bacterial infections, particularly affecting women, the elderly, and individuals with diabetes or urinary catheters. Effective management of these infections requires not only fast-acting antibiotics but also medications that maintain consistent therapeutic levels for optimal bacterial eradication.

NITROFORTIME SR 100 is a sustained release formulation of Nitrofurantoin, a trusted antibiotic with a proven track record in the treatment and prevention of lower urinary tract infections. What sets this formulation apart is its extended-release technology, which offers prolonged antibacterial action, reduces the need for multiple daily doses, and improves patient compliance.

Composition

NITROFORTIME SR 100 contains:

Nitrofurantoin 100 mg – in a sustained release tablet form.

This composition is specifically designed to ensure a steady release of the drug over time, allowing it to maintain consistent concentrations in urine, where the antibiotic exerts its full effect.

Key Features and Ingredients

🔹 Nitrofurantoin (100 mg – Sustained Release)

Belongs to the nitrofuran class of antibiotics.
Works by inhibiting bacterial enzymes involved in DNA, RNA, and protein synthesis, leading to bacterial death.
Particularly effective against common urinary pathogens, including E. coli, Enterococci, Staphylococcus saprophyticus, and some species of Klebsiella and Enterobacter.
Its sustained release mechanism ensures that therapeutic levels are maintained for a longer duration within the urinary tract.
Provides bactericidal activity rather than just bacteriostatic effects, making it suitable for both treatment and prophylaxis.

Usage Guidelines

📌 Dosage and Administration

Typically prescribed as one tablet once or twice daily, depending on the severity of infection and patient response.
Should be taken with food to enhance absorption and reduce the risk of gastrointestinal side effects.
Patients are encouraged to complete the full course, even if symptoms improve, to prevent relapse or antibiotic resistance.

📌 Important Considerations

Ensure adequate hydration throughout treatment to help flush the urinary tract and aid drug delivery.
Not recommended for use in patients with severely impaired kidney function.
Should be avoided during late pregnancy (at term) and in infants under one month of age.
Always use under medical supervision, especially in patients with chronic diseases or frequent infections.

Clinical Benefits

✅ 1. Prolonged Antibacterial Effect

Thanks to its sustained release technology, NITROFORTIME SR 100 maintains therapeutic concentrations in the urine for extended periods, enhancing the effectiveness of treatment while minimizing fluctuations in drug levels.

✅ 2. High Efficacy Against UTI Pathogens

This formulation is highly effective in eliminating Gram-negative and Gram-positive uropathogens, particularly Escherichia coli, the most common cause of UTIs.

✅ 3. Reduced Dosing Frequency

Compared to traditional Nitrofurantoin formulations, the sustained release tablet requires fewer doses per day, leading to better patient adherence and improved treatment outcomes.

✅ 4. Lower Risk of Resistance

Because it is concentrated in the urine and minimally absorbed systemically, the risk of developing systemic antibiotic resistance is low, making it ideal for long-term prophylaxis in recurrent UTI patients.

✅ 5. Well-Tolerated Profile

With fewer gastrointestinal side effects due to its gradual absorption, NITROFORTIME SR 100 is generally well tolerated, especially when taken with meals.

Who Can Benefit from NITROFORTIME SR 100?

Women with recurrent UTIs
Elderly patients prone to infections due to catheter use or reduced immunity
Individuals with diabetes, a known risk factor for UTIs
Patients needing prophylactic treatment before urological procedures
Those seeking a low-dose, long-term solution with reduced side effects

Conclusion

NITROFORTIME SR 100 offers a smart, modern solution for managing urinary tract infections with greater convenience and enhanced efficacy. By delivering the proven power of Nitrofurantoin through sustained release technology, it ensures consistent drug levels, fewer doses, and better treatment outcomes.Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options. The company offers a wide range of healthcare products, catering to various medical needs, from rare disease treatments to essential healthcare products. Sterispharma's product range includes solutions for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. Medicines can be conveniently ordered via Our websites—Sterisonline, Sterisindia, and Sterispharma.