Obeticholic acid: View Uses, Side Effects and Medi...

Composition of Obeticholic Acid

OB-COLLAR 10 contains Obeticholic Acid (10mg) as its active ingredient. Obeticholic Acid works by activating the farnesoid X receptor (FXR), a receptor that plays a critical role in regulating bile acids, fat metabolism, and liver function. By activating FXR, Obeticholic Acid helps to reduce liver inflammation, improve bile acid metabolism, and prevent the buildup of toxic bile acids in the liver, which can contribute to liver damage in conditions like primary biliary cholangitis.

• Active Ingredient: Obeticholic Acid (10mg)
• Tablet Strength: 10mg per tablet
• Other Ingredients: The tablet also contains inactive ingredients that stabilize and facilitate the absorption of Obeticholic Acid in the body.

Key Features and Ingredients

1. Active Ingredient: Obeticholic Acid
   Obeticholic Acid is a synthetic bile acid analogue that activates the farnesoid X receptor (FXR) in the liver. FXR activation helps regulate bile acid synthesis, improve lipid metabolism, and reduce liver inflammation. This makes Obeticholic Acid a powerful treatment option for individuals suffering from liver diseases like primary biliary cholangitis (PBC), a chronic autoimmune liver disease.

2. 10mg Dosage
   Each tablet of OB-COLLAR 10 contains 10mg of Obeticholic Acid, providing an appropriate dose for managing liver inflammation and improving liver function. The dosage can be adjusted based on individual patient needs and response to treatment.

3. Bile Acid Regulation
   By acting on the FXR receptor, Obeticholic Acid regulates the synthesis and flow of bile acids, which are essential for digestion and the removal of toxins from the liver. It reduces the toxic effects of accumulated bile acids, which can damage liver cells and lead to conditions like PBC.

4. Convenient Oral Tablet
   OB-COLLAR 10 comes in an easy-to-use oral tablet form, which allows patients to incorporate it seamlessly into their daily medication regimen. The tablet is designed for effective absorption to provide long-term benefits in managing liver diseases.

Usage of Obeticholic Acid

OB-COLLAR 10 is primarily used for the following medical conditions:

• Primary Biliary Cholangitis (PBC):
  Obeticholic Acid is most commonly prescribed to treat primary biliary cholangitis (PBC), a chronic autoimmune liver disease that causes progressive damage to the bile ducts. This condition results in the buildup of bile acids in the liver, leading to inflammation, scarring, and ultimately liver failure. OB-COLLAR 10 helps reduce bile acid levels, improve liver function, and slow the progression of liver damage.

• Non-Alcoholic Steatohepatitis (NASH):
  Obeticholic Acid has also shown promise in treating non-alcoholic steatohepatitis (NASH), a liver disease characterized by fat accumulation, inflammation, and liver damage. The drug works by improving liver function, reducing inflammation, and managing fat buildup in the liver.

• Cholestatic Liver Diseases:
  In conditions where bile flow is impaired, such as cholestasis, Obeticholic Acid helps to regulate bile acid levels, reduce liver damage, and improve the flow of bile, thus offering relief from symptoms.

Dosage and Administration:
The typical starting dose of OB-COLLAR 10 is 10mg once daily, which may be adjusted depending on the patient\'s response and tolerance to treatment. It is essential to follow your healthcare provider\'s instructions and attend regular check-ups to monitor liver function and treatment progress.

Benefits of Obeticholic Acid

1. Reduces Liver Inflammation
   One of the primary benefits of OB-COLLAR 10 is its ability to reduce liver inflammation caused by conditions like primary biliary cholangitis (PBC) and non-alcoholic steatohepatitis (NASH). By regulating bile acid levels and activating farnesoid X receptors (FXR), Obeticholic Acid reduces the inflammatory response in the liver, preventing further liver damage.

2. Improves Liver Function
   OB-COLLAR 10 plays a key role in improving liver function by regulating bile acid synthesis and flow. This results in a healthier liver environment, reducing the burden of toxic bile acid accumulation, which can impair liver function and lead to liver failure over time.

3. Slows the Progression of Liver Diseases
   By reducing bile acid toxicity and improving liver health, OB-COLLAR 10 can help slow the progression of liver diseases like primary biliary cholangitis (PBC) and non-alcoholic steatohepatitis (NASH). It helps preserve liver function, which can significantly improve the patient\'s quality of life.

4. Prevents Bile Acid Accumulation
   One of the key actions of Obeticholic Acid is its ability to prevent bile acid accumulation in the liver. In diseases like PBC, bile acids build up in the liver, leading to inflammation and damage. OB-COLLAR 10 helps manage bile acid levels, reducing the toxic effects and supporting overall liver health.

5. Supports Long-Term Liver Health
   Regular use of OB-COLLAR 10 helps to maintain long-term liver health by reducing inflammation, improving liver function, and preventing the buildup of harmful bile acids. It offers a more effective treatment option for individuals suffering from chronic liver conditions.

6. Well-Tolerated with Proper Monitoring
   OB-COLLAR 10 is generally well tolerated when used under medical supervision. As with any medication, it is essential to have regular liver function tests and follow your healthcare provider\'s instructions for optimal results and minimal side effects.

Conclusion

OB-COLLAR 10, with its active ingredient Obeticholic Acid (10mg), is a significant advancement in the treatment of liver diseases such as primary biliary cholangitis (PBC) and non-alcoholic steatohepatitis (NASH). By regulating bile acid metabolism and reducing liver inflammation, OB-COLLAR 10 helps improve liver function, prevent further liver damage, and slow the progression of chronic liver conditions.Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options. The company offers a wide range of healthcare products, catering to various medical needs, from rare disease treatments to essential healthcare products. Sterispharma\'s product range includes solutions for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. Medicines can be conveniently ordered via Our websites—Sterisonline, Sterisindia, and Sterispharma.