Bosentan 125 mg | BOSENTIME 125

Description

BOSENTIME 125 is a high-quality formulation containing Bosentan 125 mg, an Endothelin Receptor Antagonist (ERA) widely used in the management of Pulmonary Arterial Hypertension (PAH). PAH is a progressive condition characterized by high blood pressure in the arteries of the lungs, leading to shortness of breath, fatigue, and reduced exercise capacity. BOSENTIME 125 works by blocking the action of endothelin-1, a naturally occurring substance that causes blood vessels to constrict. By relaxing the pulmonary blood vessels, BOSENTIME 125 helps reduce the pressure within the lungs, improves oxygen flow, and enhances overall heart and lung function. This medicine is typically used as part of long-term therapy and is recognized for its proven clinical benefits in PAH management. Uses BOSENTIME 125 is primarily prescribed for the following conditions: Pulmonary Arterial Hypertension (PAH): Helps lower blood pressure in the lungs, improving physical capacity and slowing disease progression. WHO Functional Class II–III PAH Patients: Enhances exercise tolerance and reduces PAH-related symptoms. Idiopathic or Heritable PAH: Useful for patients diagnosed without a clear underlying cause. PAH Associated with Connective Tissue Diseases: Provides effective symptom control in conditions like Scleroderma. Vascular Remodeling Management: Helps prevent thickening of blood vessels in the lungs, promoting better long-term outcomes. Benefits BOSENTIME 125 offers several important therapeutic advantages: Improves Exercise Tolerance: Helps patients perform daily activities with less breathlessness and fatigue. Reduces Pulmonary Blood Pressure: Supports better lung-heart circulation by relaxing pulmonary arteries. Slows Disease Progression: Assists in preventing further damage to lung blood vessels when used consistently. Enhances Quality of Life: Reduces chronic symptoms such as chest discomfort, tiredness, and shortness of breath. Works as a Long-Term Therapy: Suitable for chronic management under medical supervision. Can Be Used in Combination Therapy: Often prescribed along with other PAH medicines for enhanced therapeutic effect. Improves Survival Rates in PAH Patients: Due to its effective hemodynamic benefits, it contributes to improved patient outcomes. Dosage The usual recommended dose of BOSENTIME 125 is one tablet twice a day, or as directed by the physician. Treatment often begins with a lower dose, gradually increasing to the therapeutic dose depending on patient tolerance. Tablets should be swallowed whole with water and can be taken with or without food. Do not break, crush, or chew the tablet. Continue treatment regularly, as BOSENTIME 125 is designed for long-term PAH management. Never adjust the dose without consulting your doctor. If a dose is missed, take it as soon as you remember unless it is close to the time for the next dose. Side Effects Like all medicines, BOSENTIME 125 may cause side effects, though not everyone experiences them. Common side effects include: Headache Flushing or warm sensation Swelling of hands, legs, or ankles (fluid retention) Low blood pressure Liver enzyme elevation Nasal congestion Tiredness or weakness Anemia (low red blood cell count) Rare but serious side effects may include: Liver damage Breathing difficulty Severe swelling or rapid weight gain Regular monitoring is essential, especially liver function tests and hemoglobin levels. Precautions and Warning Liver Safety: Bosentan may affect liver function; routine liver function tests are mandatory. Pregnancy Risk: Not recommended during pregnancy; effective contraception is required for women of childbearing age. Heart Conditions: Patients with severe heart problems should use BOSENTIME 125 cautiously. Kidney Impairment: Dose adjustment may be needed for patients with renal issues. Avoid Alcohol: Alcohol can increase the risk of liver-related side effects. Inform your doctor if you have: Liver disease Heart failure Anemia Hypotension Edema Do not combine BOSENTIME 125 with cyclosporine or glyburide due to potential drug interactions. Always use under strict medical supervision. Conclusion BOSENTIME 125 containing Bosentan 125 mg is a vital medication for the long-term management of Pulmonary Arterial Hypertension. By improving blood flow in the lungs, reducing pressure in pulmonary arteries, and enhancing exercise tolerance, it significantly improves a patient’s quality of life. When used consistently under medical supervision, BOSENTIME 125 plays an essential role in slowing PAH progression and optimizing heart-lung function. With proper monitoring and adherence to prescribed dosage, BOSENTIME 125 is a reliable and effective therapeutic option for PAH patients.