NICOMALOM 4 contains Nicoumalone 4mg, an oral anticoagulant used to prevent and treat harmful blood clots in the body. Belonging to the class of Vitamin K antagonists, NICOMALOM 4 works by thinning the blood and reducing the risk of serious cardiovascular events such as stroke, deep vein thrombosis (DVT), and pulmonary embolism (PE). It is commonly prescribed for patients with heart valve disorders, atrial fibrillation, or a history of thromboembolism. What is Nicoumalone 4mg? Nicoumalone, also known as Acenocoumarol, is a Vitamin K antagonist that interferes with the synthesis of clotting factors in the liver. It helps prevent abnormal blood clot formation by reducing the activity of vitamin K, which is essential for blood coagulation. Tab Nicoumalone is a prescription medication and should be taken under strict medical supervision due to its narrow therapeutic range and interaction potential. Nicoumalone tablets IP are widely used in long-term anticoagulation therapy. Nicoumalone Tablet Uses NICOMALOM 4 is prescribed for: Prevention and treatment of deep vein thrombosis (DVT) Management of pulmonary embolism (PE) Stroke prevention in patients with atrial fibrillation Thrombosis prevention in patients with mechanical heart valves Post-surgical clot prevention in high-risk patients These nicoumalone tablet uses are part of comprehensive care plans to reduce clot-related complications in high-risk individuals. Nicoumalone Mechanism of Action The nicoumalone mechanism of action involves inhibition of Vitamin K epoxide reductase, an enzyme required to activate clotting factors II, VII, IX, and X. By blocking this enzyme, nicoumalone tablets reduce the formation of active clotting factors, thereby preventing the blood from forming dangerous clots. ⚙️ This makes tab nicoumalone highly effective in long-term anticoagulation management. Side Effects of Nicoumalone Tablet While nicoumalone 4mg is effective, it may cause side effects such as: Easy bruising or prolonged bleeding Gum or nosebleeds Blood in urine or stool Fatigue or weakness Nausea Hair loss (rare) Skin rashes or itching Severe bleeding may occur if dosage is not properly managed. Regular INR (International Normalized Ratio) monitoring is necessary during treatment to maintain safe anticoagulation levels. Precautions Before Using NICOMALOM 4 Before using NICOMALOM 4, consider the following precautions: Frequent INR Testing: Essential to avoid bleeding or clotting risks. Liver/Kidney Issues: Use cautiously in patients with hepatic or renal impairment. Pregnancy: Contraindicated in pregnancy; can cause birth defects. Surgery/Dental Procedures: Inform your doctor or dentist about nicoumalone use beforehand. Alcohol Consumption: Should be limited, as it may affect clotting. Avoid activities that may lead to injury or bruising while on nicoumalone tablets. Drug Interactions – What Drugs Interact with Nicoumalone? Several medications can alter the effects of nicoumalone 4mg, leading to either increased bleeding or reduced anticoagulant action: NSAIDs (e.g., ibuprofen, aspirin) – increase bleeding risk Antibiotics (e.g., erythromycin, ciprofloxacin) – may elevate INR Antiepileptics (e.g., phenytoin, carbamazepine) – may decrease efficacy Herbal supplements (e.g., ginseng, St. John's Wort, ginkgo biloba) – can interfere with clotting Antifungals and thyroid medications – may enhance effects Always inform your doctor about all medications, including over-the-counter products and herbal remedies, before starting tab nicoumalone. Conclusion NICOMALOM 4 with Nicoumalone 4mg is a trusted oral anticoagulant that plays a vital role in preventing life-threatening clot-related conditions. It works by blocking the vitamin K-dependent clotting pathway, making it a valuable part of long-term blood clot prevention strategies. For safe and effective use, close monitoring and adherence to prescribed dosage are crucial. Whether for stroke prevention or post-surgical care, NICOMALOM 4 helps safeguard your vascular health with proven efficacy.
| Actuve ingredient | Nicoumalone 4mg |
| Brand name | NICOMALOM 4 |
| Manufactured by | Steris Healthcare PVT.LTD |
| Package SIZE | 10 Tablets |
| Dosage | AS directed by the Physician |
| Storage | Store in A Cool & Dry Place |
| Country of Origin | INDIA |