Sitagliptin (50mg), Metformin Hydrochloride (500mg) & Glimepiride (2mg)

Description

ST GLIPTIN GM is an advanced triple combination oral antidiabetic medication designed to help manage Type 2 Diabetes Mellitus effectively. It combines three well-established antidiabetic agents — Sitagliptin, Metformin Hydrochloride, and Glimepiride — which work together to control blood sugar levels through complementary mechanisms. This combination offers better glycemic control, reduces post-meal glucose spikes, and helps improve insulin sensitivity, making it ideal for patients who require more than one oral antidiabetic agent to maintain stable blood sugar levels. Composition Overview Sitagliptin 50mg – A DPP-4 inhibitor that increases the levels of incretin hormones, helping the body release more insulin and reduce glucose production by the liver. Metformin Hydrochloride 500mg – A biguanide that reduces hepatic glucose production and improves insulin sensitivity in peripheral tissues. Glimepiride 2mg – A sulfonylurea that stimulates pancreatic beta cells to produce more insulin. Together, these components target different pathways in glucose metabolism to achieve optimal control. How ST GLIPTIN GM Works ST GLIPTIN GM helps control blood sugar levels through a three-way action: Sitagliptin enhances the incretin system, promoting insulin release and decreasing glucagon secretion. Metformin lowers glucose production in the liver and improves insulin sensitivity. Glimepiride stimulates the pancreas to secrete insulin when blood sugar levels are high. This synergistic mechanism helps patients achieve steady blood sugar levels throughout the day while minimizing glucose fluctuations. Uses of ST GLIPTIN GM ST GLIPTIN GM is used for: Management of Type 2 Diabetes Mellitus in adults. Patients inadequately controlled on metformin, glimepiride, or sitagliptin alone. Reducing fasting and postprandial blood glucose levels. Dosage and Administration The dosage of ST GLIPTIN GM should be prescribed by a healthcare professional based on individual needs and blood glucose response. Typically taken once daily with meals to minimize gastrointestinal side effects. It is important to maintain a consistent schedule and continue regular blood sugar monitoring. Do not crush or chew the tablets. Swallow whole with water. Key Benefits Triple-action control for effective diabetes management. Improves insulin secretion and reduces liver glucose output. Decreases post-meal sugar spikes for better day-long control. Supports weight balance and improves overall metabolic function. Convenient once-daily dosing for better patient compliance. Side Effects Common side effects may include: Mild gastrointestinal symptoms such as nausea, diarrhea, or abdominal discomfort Headache or dizziness Hypoglycemia, especially if meals are skipped Rarely, allergic skin reactions or metallic taste Always consult your doctor if side effects persist or worsen. Precautions and Warnings Avoid use in patients with severe kidney or liver impairment. Not recommended for Type 1 Diabetes Mellitus or diabetic ketoacidosis. Take with food to reduce stomach irritation. Avoid alcohol as it may increase the risk of lactic acidosis. Pregnant or breastfeeding women should take this medication only under medical supervision. Drug Interactions May interact with beta-blockers, insulin, and other oral hypoglycemic agents. Use caution when combined with diuretics or ACE inhibitors. Conclusion ST GLIPTIN GM by Steris Healthcare is a powerful and reliable triple-action therapy for Type 2 Diabetes Mellitus. By combining the complementary effects of Sitagliptin, Metformin, and Glimepiride, it ensures effective glycemic control, minimizes glucose fluctuations, and supports long-term metabolic health. This formulation is ideal for patients who need enhanced blood sugar management, better compliance, and sustained control throughout the day.