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FENOFIBRON 145 Fenofibrate FENOFIBRON is a lipid-lowering medication primarily used to reduce cholesterol levels and triglycerides in patients at risk of cardiovascular disease. FENOFIBRON belongs to the class of drugs known as fibrates, which work by activating peroxisome proliferator-activated receptors (PPARs). Specifically, fenofibrate activates PPARα, leading to several metabolic effects that contribute to its lipid-modifying actions. Mechanism of Action: FENOFIBRON primary mechanism involves the activation of PPARα, a type of nuclear receptor that plays a crucial role in the metabolism of lipids. Activation of PPARα: Increases the oxidation of fatty acids in the liver and muscle, reducing triglyceride levels. Enhances the synthesis of lipoprotein lipase, an enzyme that helps break down triglycerides in the bloodstream. Leads to a decrease in the production of apolipoprotein C-III (an inhibitor of lipoprotein lipase), further facilitating the reduction of triglycerides. Modifies the production of apolipoproteins, including an increase in apolipoprotein A-I and apolipoprotein A-II, contributing to the increase in high-density lipoprotein (HDL) cholesterol, often referred to as "good" cholesterol. Indications: FENOFIBRON is used to treat several types of dyslipidemia, including: Hypertriglyceridemia (high levels of triglycerides in the blood). Mixed dyslipidemia, characterized by elevated levels of low-density lipoprotein (LDL) cholesterol and triglycerides and low levels of HDL cholesterol. Primary hypercholesterolemia or mixed dyslipidemia as an adjunct to diet when the response to diet and other nonpharmacological measures alone have been inadequate. For further information please contact: info@sterispharma.com / contact@sterispharma.com call/whatsapp: 8209542042, 8955945010, 6377716668 order now: https://www.sterisonline.com/product/fenofibron-145-133299
