GLIDAPA PIO is a combination medication used to manage Type 2 Diabetes Mellitus in adults. It helps control high blood sugar levels, thereby reducing the risk of serious diabetes-related complications such as heart disease, kidney damage, and nerve problems. The dual-action formula of Dapagliflozin and Pioglitazone offers effective glycemic control by targeting different pathways of glucose metabolism. Key Ingredients Dapagliflozin (10 mg) A Sodium-Glucose Co-Transporter-2 (SGLT2) inhibitor that promotes the excretion of excess glucose through urine. Pioglitazone (15 mg) A Thiazolidinedione (TZD) that improves insulin sensitivity in muscle and fat tissues, helping cells absorb glucose more efficiently. Key Benefits Helps lower elevated blood sugar levels in adults with Type 2 Diabetes. Improves insulin sensitivity, leading to better glucose uptake by body tissues. Reduces the risk of diabetes-related complications like cardiovascular issues. Promotes weight management through urinary glucose excretion. May contribute to lowering blood pressure as an additional benefit. Can be used as an adjunct to diet, exercise, and other antidiabetic medications. How Does It Work? Dapagliflozin works by inhibiting SGLT2 in the kidneys, reducing glucose reabsorption and increasing its excretion through urine, thereby lowering blood sugar levels. Pioglitazone enhances the body's sensitivity to insulin by acting on peroxisome proliferator-activated receptors (PPARs) in fat and muscle cells, improving glucose uptake and reducing insulin resistance. Together, they provide a complementary mechanism to achieve better glycemic control. Directions for Use Take GLIDAPA PIO exactly as prescribed by your healthcare provider. It is usually taken once daily, with or without food. Swallow the tablet whole with water; do not crush or chew. Maintain a healthy diet and regular exercise for optimal results. Do not stop or change the dosage without consulting your doctor. Side Effects Common side effects may include urinary tract infections, increased urination, and mild hypoglycemia (when used with other antidiabetic drugs). Weight gain, fluid retention, and swelling (edema) may occur due to pioglitazone. Possible risk of genital infections (e.g., yeast infections). Rarely, it may increase the risk of bladder infections or bone fractures. Report any unusual symptoms such as difficulty urinating, signs of heart failure (shortness of breath, sudden weight gain), or severe allergic reactions to your doctor immediately.