Combipack of Mirabegron 50 mg & Silodosin 8 mg SILODOSIA M 50 KIT is a specially designed combination therapy containing Mirabegron 50 mg and Silodosin 8 mg, formulated to provide comprehensive relief from lower urinary tract symptoms (LUTS) associated with Benign Prostatic Hyperplasia (BPH) and Overactive Bladder (OAB). This advanced dual-action therapy targets both the storage and voiding phases of urination. While Silodosin acts as a selective alpha-1 adrenergic receptor blocker that relaxes the smooth muscles in the prostate and bladder neck to improve urine flow, Mirabegron, a beta-3 adrenergic receptor agonist, enhances bladder relaxation to increase storage capacity and reduce urinary urgency. Manufactured with clinical precision, SILODOSIA M 50 KIT offers a modern, well-tolerated, and highly effective solution for men suffering from urinary difficulties caused by prostate enlargement and bladder overactivity. Uses SILODOSIA M 50 KIT is primarily prescribed for the management of urinary disorders related to prostate enlargement and bladder dysfunction. The key uses include: Benign Prostatic Hyperplasia (BPH): Helps relieve symptoms such as difficulty in starting urination, weak urine stream, dribbling after urination, and frequent nighttime urination (nocturia). Overactive Bladder (OAB): Manages symptoms like urgency, increased frequency of urination, and urge incontinence by improving bladder control. Urinary Retention and Incomplete Emptying: Reduces bladder outlet resistance and enhances the ability to completely empty the bladder. Combination Therapy for Dual Symptom Relief: The combination of Silodosin (voiding phase relief) and Mirabegron (storage phase improvement) ensures complete management of both obstructive and irritative urinary symptoms. Thus, SILODOSIA M 50 KIT is particularly effective in patients where monotherapy has failed to adequately control both bladder overactivity and prostate-induced urinary issues. Benefits SILODOSIA M 50 KIT offers several therapeutic advantages that make it a superior choice for urinary symptom management: Dual Mechanism of Action: Combines two complementary agents — Silodosin to improve urine flow and Mirabegron to increase bladder capacity — for complete urinary relief. Effective Symptom Control: Provides significant improvement in both voiding and storage symptoms, reducing frequency, urgency, and nighttime urination. Improved Quality of Life: Restores normal bladder function, reduces discomfort, and enhances daily comfort and sleep quality. Minimally Invasive Alternative: Offers a non-surgical, well-tolerated treatment option for patients with mild to moderate BPH symptoms. Long-Lasting Relief: The once-daily dosing ensures sustained symptom control throughout the day and night. Reduced Risk of Side Effects: Compared to older alpha-blockers, Silodosin shows greater selectivity for prostatic receptors, minimizing dizziness and hypotension, while Mirabegron has a favorable safety profile compared to traditional antimuscarinic drugs. Synergistic Action: Clinical studies show that the combination provides better efficacy in symptom reduction and bladder emptying compared to either drug used alone. Enhanced Bladder Compliance: Mirabegron’s effect on bladder smooth muscles increases capacity, reducing urgency and frequency of urination. In summary, SILODOSIA M 50 KIT provides holistic management of urinary symptoms with proven safety and efficacy. Dosage Recommended Dosage: Silodosin 8 mg: Once daily, preferably after a meal. Mirabegron 50 mg: Once daily, with or without food. Administration: Take both tablets orally with water. Swallow whole; do not crush or chew the tablets. Maintain consistency by taking the medicine at the same time each day. Duration of Therapy: The duration depends on the patient’s condition and response to treatment. Regular follow-up with a healthcare provider is recommended for optimal results. Side Effects While SILODOSIA M 50 KIT is generally well-tolerated, some patients may experience mild and temporary side effects such as: Dizziness or light-headedness Headache Nasal congestion or runny nose Mild increase in heart rate Constipation or dry mouth Fatigue or weakness Rare but serious side effects may include: Allergic reaction (rash, itching, or swelling) Difficulty in ejaculation (with Silodosin) Increased blood pressure (with Mirabegron) Irregular heartbeat (rare) If any severe or persistent side effects occur, consult your healthcare provider immediately.
| Composition | Combipack of Mirabegron 50 mg & Silodosin 8 mg |
| Active ingredient | Combipack of Mirabegron 50 mg & Silodosin 8 mg |
| Brand Name: | SILODOSIA M 50 |
| Storage | Store In A Cool & Dry Place |
| Dosage | As Directed By the Physician |
| Country of origin | INDIA |
| Manufactured By | Steris Healthcare Pvt Ltd |