SEIZMET G4 is a combination medicine containing Glimepiride 4 mg and Metformin Hydrochloride 500 mg, developed to support better blood sugar control in adults with Type 2 Diabetes Mellitus (T2DM). This dual therapy is widely recommended when diet, exercise, or single-drug therapy does not provide adequate glycemic control. Manufactured with a patient-centric approach, SEIZMET G4 is designed for long-term diabetes management according to Indian clinical needs. The combination works by decreasing sugar production in the liver, improving insulin response, and helping the body utilize glucose more effectively. Uses SEIZMET G4 is prescribed primarily for: Type 2 Diabetes Mellitus Improving glycemic control when lifestyle changes and monotherapy fail Reducing the risk of diabetes-related complications such as nerve damage, kidney problems, and vision issues Supporting weight control when combined with a healthy diet and physical activity It is not suitable for treating Type 1 diabetes or diabetic ketoacidosis. Benefits 1. Dual Mechanism for Strong Glycemic Control Metformin reduces liver glucose production and improves insulin sensitivity. Glimepiride stimulates the pancreas to release the right amount of insulin. Together, they help achieve smoother and more stable blood sugar levels throughout the day. 2. Helps Prevent Long-Term Complications Maintaining blood sugar within target range lowers the risk of cardiovascular disease, neuropathy, retinopathy, and kidney damage. 3. Suitable for Daily Diabetes Management The combination suits patients who require stronger therapy than Metformin alone. 4. Weight-Neutral Effect Metformin may support slight weight reduction, helping patients maintain a healthier metabolic profile. 5. Improves Insulin Efficiency By enhancing cellular response to insulin, SEIZMET G4 helps reduce insulin resistance—one of the primary challenges in Type 2 Diabetes. Dosage The dosage of SEIZMET G4 should be strictly based on your doctor’s recommendation. Usually taken once daily, preferably with meals to reduce gastric side effects. Do not skip meals after taking the tablet, as Glimepiride may cause low blood sugar if taken without food. If a dose is missed, take it soon as you remember—do not double dose. Lifestyle modifications such as regular exercise, reduced sugar intake, and balanced diet should continue alongside medication. Side Effects Most side effects are mild and may settle as your body adjusts. Common Side Effects: Nausea or stomach discomfort Diarrhoea or gas Headache Weakness or dizziness Hypoglycemia (Low Blood Sugar) may occur due to Glimepiride. Symptoms include: Sweating Shaking Hunger Fast heartbeat Blurred vision Consuming sugar or fruit juice can offer quick relief. Rare but Serious Side Effects: Lactic acidosis (linked to Metformin) Severe allergic reactions Liver or kidney dysfunction Seek immediate medical help if symptoms worsen or persist. Precautions and Warning Not recommended for pregnant or breastfeeding women unless advised by a doctor. Patients with kidney or liver problems should use SEIZMET G4 with caution. Avoid alcohol, as it may increase the risk of hypoglycemia and lactic acidosis. Regular monitoring of blood glucose, HbA1c, kidney function, and liver enzymes is essential. Inform your doctor if you are scheduled for any surgery or radiology tests involving contrast dye. Not suitable for those with Type 1 diabetes, severe dehydration, uncontrolled infection, or metabolic acidosis. Conclusion SEIZMET G4 (Glimepiride 4 mg & Metformin Hydrochloride 500 mg) is an effective and trusted combination therapy for managing Type 2 Diabetes Mellitus. By targeting insulin resistance and supporting insulin secretion, it provides comprehensive blood sugar control and helps reduce future complications. When paired with a balanced lifestyle, SEIZMET G4 can significantly improve long-term diabetes outcomes and overall metabolic health. Always follow medical guidance and routine monitoring to achieve the best therapeutic results.
| Active ingredient | Glimepiride 4 mg & Metformin Hydrochloride 500 mg |
| Brand Name | SEIZMET G4 |
| Manufactured By | Steris Healthcare Pvt Ltd |
| Package SIZE | 10x15 Tablets |
| Dosage | As Directed By the Physician |
| Storage | Store In A Cool & Dry Place |
| Country of origin | INDIA |