METAPROLATE R 25

Description

Metaprolol SR (25mg) + Ramipril (5mg) METAPROLATE R 25 is another therapeutic approach used in the management of hypertension (high blood pressure) and heart failure. METAPROLATE R 25 can also be effective in reducing the risk of cardiovascular events in patients with certain heart conditions. Let's break down the components and their synergistic benefits: Metoprolol SR (Sustained Release) Metoprolol SR provides a steady level of the beta-blocker in the bloodstream over an extended period, which is beneficial for achieving consistent blood pressure control throughout the day. It works by reducing the heart rate, the force of heart muscle contractions, and the release of renin from the kidneys, leading to lower blood pressure. Ramipril Ramipril belongs to the class of drugs known as angiotensin-converting enzyme (ACE) inhibitors. It works by inhibiting the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor, thereby lowering blood pressure. Angiotensin II also stimulates aldosterone secretion, which leads to sodium and water retention by the kidneys. By inhibiting this pathway, Ramipril facilitates the excretion of sodium and water, further lowering blood pressure. Additionally, ACE inhibitors have been shown to have protective effects on the heart and kidneys, which is particularly beneficial for patients with hypertension, diabetes, or a history of heart failure. METAPROLATE R 25 METAPROLATE R 25 allows for a more comprehensive management of hypertension by targeting different physiological pathways: Metoprolol reduces the workload on the heart and decreases the demand for oxygen by slowing down the heart rate and reducing the force of heart contractions. Ramipril enhances this effect by lowering the resistance against which the heart must pump, thanks to its vasodilatory effects. It also offers renal and cardiovascular protective benefits.