REVOSTATIN GOLD 10 Rosuvastatin (10mg), Clopidogrel (75mg) & Aspirin (75) REVOSTATIN GOLD commonly used in the management of cardiovascular diseases, each serving different roles but often used together in patients with specific conditions to reduce the risk of cardiovascular events such as heart attacks and strokes. Rosuvastatin Class: Statin (HMG-CoA reductase inhibitor) Use: Rosuvastatin is primarily used to lower cholesterol and triglycerides in the blood. It's effective in reducing the levels of “bad“ cholesterol (LDL) and triglycerides, while increasing “good“ cholesterol (HDL). It's prescribed to prevent cardiovascular disease and to manage high cholesterol. Mechanism: It works by inhibiting HMG-CoA reductase, an enzyme involved in cholesterol synthesis in the liver, thereby reducing the total amount of cholesterol produced. Side Effects: Common side effects include muscle pain, weakness, headache, abdominal pain, and nausea. Rarely, it can cause more serious muscle problems or liver issues. Clopidogrel Class: Antiplatelet agent Use: Clopidogrel is used to prevent blood clots in patients who have experienced heart attacks, strokes, or have other conditions like peripheral artery disease. It's often prescribed along with aspirin. Mechanism: It works by inhibiting platelets in the blood from clumping together, thereby reducing the risk of forming harmful clots. Side Effects: Common side effects include bleeding more easily than normal, including gastrointestinal bleeding. Bruising, diarrhea, and indigestion can also occur. Aspirin Class: Nonsteroidal anti-inflammatory drug (NSAID), antiplatelet Use: Aspirin is used for a variety of conditions including pain relief, fever reduction, and inflammation. In low doses, it's used to prevent heart attacks, strokes, and blood clot formation in people at high risk. Mechanism: Aspirin inhibits enzymes involved in the production of prostaglandins, reducing inflammation and pain at higher doses. At lower doses, it irreversibly inhibits the enzyme COX-1 in platelets, leading to reduced formation of thromboxane A2, a molecule that encourages platelet aggregation and vasoconstriction. Side Effects: Side effects can include gastrointestinal ulcers or bleeding, especially with long-term use. Low-dose aspirin is generally well tolerated but should be used under medical advice to minimize risks. Combined Use in Cardiovascular Disease Rationale: The combination of these medications is often prescribed to individuals at high risk of cardiovascular events. Rosuvastatin is used to manage cholesterol levels and reduce the risk of plaque build-up in the arteries. Clopidogrel and aspirin both work to prevent blood clots, but through slightly different mechanisms, offering a synergistic effect that is particularly beneficial in preventing heart attacks and strokes in patients with coronary artery disease or after certain procedures like stent placement. Considerations: It's important to use these medications under the guidance of a healthcare provider, as the combination can increase the risk of bleeding. The benefits of reducing cardiovascular risk need to be balanced against the potential risks, especially in individuals with a history of bleeding disorders or those taking other medications that can increase the risk of bleeding. For further information: EMAIL: info@sterispharma.com / contact@sterispharma.com CALL/WHATSAPP: 7877551268, 7849827488 Order NOW https://www.sterisonline.com/product/revostatin-gold-10-134345