CARDULES ISMN 20 is a prescription medication formulated with Isosorbide Mononitrate (20 mg), a nitrate class compound widely used to prevent and manage angina pectoris—a chest pain condition caused by reduced blood flow to the heart. This extended-release formulation is designed to provide prolonged relief from chest discomfort, improving the overall quality of life in individuals suffering from chronic heart-related conditions. By dilating the blood vessels, CARDULES ISMN 20 lowers the heart's workload and enhances oxygen delivery, making it a cornerstone in the long-term management of coronary artery disease (CAD). Key Ingredient Isosorbide Mononitrate (20 mg): A long-acting nitrate that functions as a vasodilator. It reduces cardiac oxygen demand and increases oxygen supply by relaxing and widening blood vessels. It’s particularly effective in preventing anginal attacks rather than treating them once they occur. Key Benefits Prevents Angina Episodes: Regular use reduces the frequency and severity of chest pain caused by inadequate oxygen supply to the heart. Improves Blood Circulation: By relaxing vascular smooth muscles, it enhances blood flow, especially to the heart muscle. Reduces Cardiac Workload: Decreases preload and afterload, easing the burden on the heart and lowering myocardial oxygen consumption. Long-Lasting Effect: The 20 mg dose offers sustained action, reducing the need for multiple daily doses. Enhances Exercise Tolerance: By preventing angina, it helps patients maintain a more active lifestyle without cardiac discomfort. How Does It Work? CARDULES ISMN 20 works by relaxing the smooth muscles of the blood vessels, especially in the veins. This vasodilation effect reduces the volume of blood returning to the heart (preload), and to a lesser extent, reduces the pressure against which the heart must pump (afterload). As a result, the heart requires less oxygen, helping to prevent episodes of angina. Isosorbide Mononitrate also improves coronary blood flow, ensuring the heart muscle receives adequate oxygen and nutrients. Directions for Use Dosage: As prescribed by the physician, typically one tablet (20 mg) once or twice daily depending on the severity of symptoms and individual patient response. Administration: Take the tablet orally with water, preferably after meals to avoid gastrointestinal discomfort. Do Not Crush or Chew: Swallow the tablet whole to ensure proper drug release and absorption. Timing Matters: It’s recommended to follow a nitrate-free interval (usually 10–14 hours) daily to prevent nitrate tolerance (reduced effectiveness over time). Consistency is Key: Take at the same time each day to maintain effective blood levels. Missed Dose: If a dose is missed, take it as soon as possible. If it's near the time of the next dose, skip the missed one—do not double dose. Side Effects Like all medications, CARDULES ISMN 20 may cause side effects, though not everyone experiences them. Common side effects include: Common Side Effects: Headache (usually subsides with continued use) Dizziness or light-headedness Flushing (warmth, redness, or tingling) Low blood pressure (hypotension) Fatigue or weakness Serious Side Effects (Rare but Require Immediate Medical Attention): Fainting or severe dizziness Rapid heartbeat (tachycardia) Allergic reactions (rash, itching/swelling, severe dizziness, trouble breathing) Worsening angina (especially if the drug is suddenly stopped) Precautions & Warnings Do Not Use with other nitrate medications (e.g., nitroglycerin) or phosphodiesterase inhibitors (e.g., sildenafil, tadalafil) due to the risk of severe hypotension. Use caution in patients with hypotension, anemia, or glaucoma. Consult a doctor before use during pregnancy or breastfeeding. Avoid sudden position changes (e.g., sitting to standing) to reduce dizziness or fainting. Storage Information Store in a cool, dry place below 25°C. Keep away from moisture and direct sunlight. Keep out of reach of children.