FLUTICATONE AZF spray is used to treat an itchy or runny nose, sneezing, or other symptoms caused by seasonal hay fever. Nasal FLUTICATONE AZF AZF is used to relieve seasonal allergy symptoms of the nose such as stuffy/runny nose, itching, sneezing, and post-nasal drip. Nasal FLUTICATONE AZF AZF is a combination of two medicine, Azelastine Hydrochlordie and Fluticasone Furoate. Fluticatone AZF is an antihistamine. FLUTICATONE AZF AZF works by preventing the effects of a substance called histamine, which is produced by the body.