Enzalutamide 160 mg Tablet: View Uses, Benefits, Price, Side Effects and More.
Enzalutamide 160 mg tablet is a powerful oral medication used in the treatment of prostate cancer. It belongs to a class of drugs known as androgen receptor inhibitors and plays a significant role in improving survival outcomes in men with advanced or metastatic prostate cancer. With growing clinical evidence and real-world success, Enzalutamide 160 mg has become a cornerstone of hormone therapy in oncology.
In this article, we’ll explore the uses, benefits, price, mechanism of action, and potential side effects of Enzalutamide 160 mg, and offer guidance for patients and caregivers navigating advanced prostate cancer therapy.
What is Enzalutamide 160 mg?
Enzalutamide is a nonsteroidal antiandrogen (NSAA) that inhibits androgen receptors. Androgens, including testosterone, promote the proliferation of prostate cancer cells. Enzalutamide 160 mg tablet successfully slows or stops tumor development by inhibiting these receptors, including in individuals with castration-resistant prostate cancer (CRPC).
The US FDA and DCGI have approved Enzalutamide as a standard-of-care medication in:
Metastatic castration-resistant prostate carcinoma (mCRPC)
Nonmetastatic CRPC
Metastatic hormone-sensitive prostate carcinoma (mHSPC)
It may be taken alone or in conjunction with other hormone-lowering medications.
Enzalutamide 160 mg Tablet: Key Benefits
The 160 mg dosage is the standard daily dose of Enzalutamide. Taken once daily, this medication offers several critical benefits in prostate cancer management:
1. Delays Disease Progression
Enzalutamide 160 mg has demonstrated its ability to delay metastasis, slow tumor growth, and prolong progression-free survival (PFS) in both metastatic and non-metastatic cases.
2. Improves Overall Survival
Clinical trials like PROSPER, PREVAIL, and AFFIRM have shown that patients on Enzalutamide 160 mg experience longer overall survival (OS), even when cancer is resistant to standard androgen deprivation therapy (ADT).
3. Better Quality of Life
Unlike chemotherapy, Enzalutamide is a well-tolerated oral option that preserves daily functioning and minimizes hospital visits.
4. Non-Cytotoxic and Convenient
As an oral, non-chemotherapy drug, Enzalutamide 160 mg offers convenience for long-term use, especially in elderly patients or those with poor chemotherapy tolerance.
Enzalutamide 160 mg Tablet Uses
The clinical enzalutamide 160 mg uses include a wide spectrum of prostate cancer stages and types:
1. Castration-Resistant Prostate Cancer (CRPC)
For patients whose prostate cancer continues to grow despite testosterone suppression, Enzalutamide offers effective secondary hormonal therapy.
2. Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)
Used alongside ADT, Enzalutamide 160 mg enhances the suppression of cancer progression even in early metastatic disease.
3. Non-Metastatic CRPC
In patients without detectable metastases but with rising PSA levels, Enzalutamide helps delay metastasis and offers better long-term control.
4. Post-Chemotherapy Management
For patients previously treated with docetaxel, Enzalutamide helps in disease control and survival extension.
How Enzalutamide 160 mg Works
Unlike older antiandrogens, Enzalutamide works at multiple points in the androgen receptor signaling pathway:
Blocks androgen binding to the androgen receptor.
Prevents nuclear translocation of the receptor.
Inhibits DNA binding and subsequent gene expression.
This triple mechanism ensures superior androgen blockade, making it more effective than older agents like bicalutamide.
Dosage & Administration of Enzalutamide 160 mg Tablet
The standard recommended dose of Enzalutamide is:
160 mg once daily, taken orally
Can be taken with or without food
Usually prescribed as four 40 mg tablets or one 160 mg tablet
Important Guidelines:
Take the dose at the same time each day for best results.
Do not chew, crush, or break the tablet.
Continue treatment as prescribed, even if symptoms improve.
Do not stop without consulting your oncologist.
Enzalutamide 160 mg Side Effects
While generally well-tolerated, enzalutamide 160 mg side effects may occur, especially in long-term users.
Common Side Effects:
Fatigue
Weakness
Hot flashes
Back pain
Hypertension
Constipation
Diarrhea
Serious Side Effects (Rare):
Seizures (especially in patients with history of brain disorders)
Falls or fractures
Cognitive disturbances (memory or attention issues)
Liver enzyme elevation
Cardiovascular risks
If side effects are severe or persistent, dose modification or treatment interruption may be required.
Tab Enzalutamide 160 mg Price in India
Tab Enzalutamide 160 mg price varies depending on the brand, manufacturer, and whether it’s an innovator or a generic version.
Price Range:
Generic Enzalutamide 160 mg tablets in India: ₹12,000 – ₹25,000 per pack (30 tablets)
Branded versions (e.g., Xtandi®): ₹65,000 – ₹85,000 per month
Several Indian pharmaceutical companies like Steris Healthcare, Glenmark, Zydus, and Hetero manufacture cost-effective, quality-assured generics that are DCGI-approved and WHO-GMP certified.
Why Choose Enzalutamide 160 mg from Steris Healthcare?
Steris Healthcare Pvt Ltd is a reputed Indian pharmaceutical manufacturer, offering high-quality, affordable oncology medications including Enzalutamide 160 mg tablets. Manufactured in WHO-GMP and ISO-certified facilities, Steris Healthcare ensures:
Stringent quality control
Clinical-grade efficacy
Patient-centric affordability
Reliable distribution across India
Their generic Enzalutamide 160 mg is trusted by oncologists for its consistent bioavailability and clinical performance.
