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Fluticasone Furoate and Vilanterol Powder for Inhalation – Uses, Benefits, Dosage & Side Effects

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Introduction

FLUTICATONE VILO 200 is an advanced inhalation therapy that contains fluticasone furoate and vilanterol powder for inhalation, designed for the long-term management of asthma and chronic obstructive pulmonary disease (COPD). This combination delivers both anti-inflammatory and bronchodilatory benefits, providing improved breathing and reduced symptoms.

Mechanism of Action

  1. Fluticasone Furoate

    • A potent inhaled corticosteroid (ICS).

    • Reduces inflammation in the airways by inhibiting inflammatory mediators and immune responses.

    • Helps prevent swelling, mucus production, and airway narrowing.

  2. Vilanterol

    • A long-acting β2-adrenergic agonist (LABA).

    • Relaxes smooth muscle in the airways, providing prolonged bronchodilation.

    • Improves airflow and reduces breathing difficulty for up to 24 hours.

Synergistic Effect: The corticosteroid component addresses inflammation, while the LABA component maintains open airways, ensuring comprehensive control over chronic respiratory diseases.

Uses and Indications

FLUTICATONE VILO 200 is indicated for:

  • Maintenance treatment of asthma in adults and adolescents (not for acute relief)

  • Long-term management of COPD, including chronic bronchitis and emphysema

  • Reducing the frequency of asthma and COPD exacerbations

  • Improving lung function in patients with persistent respiratory symptoms

Efficacy and Clinical Evidence

  • Proven Symptom Control: Clinical trials show significant improvement in FEV₁ (Forced Expiratory Volume in 1 second) after consistent use.

  • Once-Daily Dosing: Ensures better patient adherence due to its 24-hour effect.

  • Reduced Exacerbations: Fewer hospitalizations and flare-ups reported among patients using this combination compared to monotherapy.

  • Quality of Life: Patients experience better exercise tolerance and reduced nighttime symptoms.

Side Effects and Safety Profile

Common Side Effects:

  • Headache

  • Throat irritation

  • Hoarseness

  • Cough

  • Nasal congestion

Less Common but Serious Side Effects:

  • Increased risk of pneumonia (in COPD patients)

  • Allergic reactions (rash, swelling, difficulty breathing)

  • Paradoxical bronchospasm (rare)

  • Adrenal suppression with prolonged high-dose use

Safety Tips: Rinse mouth after each use to prevent oral thrush.

Contraindications and Precautions

Contraindications:

  • Hypersensitivity to fluticasone furoate or vilanterol

  • Primary treatment of acute asthma or severe bronchospasm

Precautions:

  • Not recommended for children under 12 years unless prescribed by a specialist

  • Use cautiously in patients with cardiovascular disorders, diabetes, thyroid problems, or immunosuppression

  • Pregnant or breastfeeding women should consult their doctor before use

Drug Interactions

  • Beta-blockers: May reduce bronchodilatory effect

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir): May increase systemic corticosteroid exposure

  • Other long-acting β2 agonists: Risk of overdose and side effects

  • Immunosuppressants: May increase infection risk

Warnings and Regulatory Status

  • Prescription-only medicine for maintenance therapy of asthma and COPD

  • Not to be used as a rescue inhaler for sudden symptoms

  • Overuse may lead to cardiovascular and systemic corticosteroid side effects

  • Manufactured under strict WHO-GMP compliance standards

Patient Advice and Tips

  • Always use fluticasone furoate and vilanterol powder for inhalation as prescribed by your doctor

  • Inhale deeply and steadily through the inhaler for full dose delivery

  • Rinse mouth after inhalation to reduce the risk of oral thrush

  • Do not stop abruptly without medical advice, as symptoms may worsen

  • Keep track of inhaler doses to ensure timely refill

Availability

FLUTICATONE VILO 200 is available in pre-metered dry powder inhaler (DPI) form for once-daily use. Distributed by Steris Healthcare Pvt Ltd, it is accessible across India with WHO-GMP-certified manufacturing quality.

Frequently Asked Questions

1. What are fluticasone furoate and vilanterol powder for inhalation uses?
It is used for the maintenance treatment of asthma and COPD, improving breathing and reducing flare-ups.

2. Can this medicine be used during an asthma attack?
No, it is not a rescue medication; it is meant for long-term control.

3. Is fluticasone furoate a steroid?
Yes, it is an inhaled corticosteroid that reduces airway inflammation.

4. How soon can I expect results?
Symptom improvement may be noticed within a few days, but maximum benefit is seen after regular use for several weeks.

5. Why choose Steris Healthcare Pvt Ltd for this medicine?
Steris Healthcare Pvt Ltd ensures WHO-GMP-certified quality, affordability, wide availability, and patient-focused respiratory solutions.

Why Choose Steris Healthcare Pvt Ltd?

Steris Healthcare Pvt Ltd is committed to delivering high-quality respiratory medicines like FLUTICATONE VILO 200. Their advanced manufacturing facilities, rigorous quality control, and patient-first approach ensure reliable and effective treatment options for asthma and COPD.

Conclusion

FLUTICATONE VILO 200 combines the power of fluticasone furoate and vilanterol powder for inhalation to deliver long-term control of asthma and COPD. With its anti-inflammatory and bronchodilatory action, once-daily dosing, and proven clinical effectiveness, it offers patients an improved quality of life and better respiratory health when used as prescribed.

 2025-08-08T06:43:06