Introduction
STARGAB 300 is a pharmaceutical product containing Gabapentin 300 mg, a well-established medication commonly known as tab gabapentin 300 mg, gabapentin 300 mg tablet, or simply gabapentin 300 mg. Manufactured by Steris Healthcare Pvt Ltd, STARGAB 300 is recognized for its reliability and high-quality standards. Gabapentin 300 mg plays a crucial role in the management of epilepsy, neuropathic pain, and restless leg syndrome, making it a staple in neurological treatment protocols.
Mechanism of Action
Gabapentin 300 mg acts by binding to the α2δ subunit of voltage-dependent calcium channels in the central nervous system. This action regulates abnormal electrical activity and reduces the release of excitatory neurotransmitters involved in pain pathways and seizure initiation. Gabapentin does not directly affect GABA receptors but influences GABA and glutamate synthesis, contributing to its anticonvulsant and analgesic effects.
Uses and Indications
Gabapentin 300 mg is indicated for:
Epilepsy: As adjunct therapy for controlling partial seizures.
Neuropathic Pain: Effective for conditions like peripheral neuropathy, postherpetic neuralgia, and diabetic neuropathy.
Restless Leg Syndrome (RLS): Reduces unpleasant sensations in the legs and improves sleep quality.
Additional Uses: Sometimes prescribed for fibromyalgia and carpal tunnel syndrome off-label.
Efficacy and Clinical Evidence
Clinical studies show that Gabapentin 300 mg significantly reduces neuropathic pain and seizure frequency. Trials demonstrate meaningful improvements in pain scores and functional outcomes in conditions like carpal tunnel syndrome, with the 300 mg dose being more effective than lower doses and well-tolerated by most patients. Its use as adjunct therapy in epilepsy and neuropathic syndromes is widely supported and recommended in various guidelines.
Side Effects and Safety Profile
Gabapentin 300 mg side effects include:
Drowsiness, dizziness, tiredness
Nausea, vomiting, constipation or diarrhea
Weight gain, increased appetite
Swelling of hands/feet, blurred or double vision
Headache, unsteadiness, anxiety, memory problems
Rare serious effects: rash, allergic reactions, breathing difficulties, suicidal thoughts
Most side effects are mild and improve as your body adjusts. However, serious symptoms need immediate medical attention.
Contraindications and Precautions
Gabapentin 300 mg should be avoided in patients with:
Previous allergic reaction to gabapentin or its excipients
History of gabapentin misuse or addiction
Myasthenia gravis or myoclonus disorders
Caution is necessary in the elderly, patients with renal impairment, and those prone to respiratory depression.
Drug Interactions
Gabapentin can interact with:
CNS depressants (e.g., opioids, sedatives): Increased risk of drowsiness, respiratory depression.
Certain antacids (e.g., containing magnesium/aluminum): Reduced absorption—space doses apart.
Multiple medicines: Over 271 potential drug interactions, with some major, moderate, or minor significance.
Alcohol may intensify drowsiness and other CNS effects, so avoid consuming alcohol during therapy.
Warnings and Regulatory Status
Regulation: In the UK and several regions, gabapentin is classified as a Schedule 3 controlled substance due to risks of misuse and dependence.
FDA Warning: Risk of respiratory depression—especially when combined with CNS depressants, opioids, or in vulnerable patients.
Careful monitoring for signs of abuse or dependence is advised.
Patient Advice and Tips
Take gabapentin 300 mg tablet as prescribed, with or without food.
Do not suddenly stop treatment without medical supervision; abrupt withdrawal can increase seizure risk.
If you miss a dose, take it as soon as you remember unless it's close to the next dose.
Store tablets at room temperature, away from moisture and light.
Report any new or worsening symptoms to your healthcare provider promptly.
Availability
STARGAB 300 is manufactured and marketed by Steris Healthcare Pvt Ltd and is available across pharmacies in India. For bulk purchase or distribution inquiries, contact Steris Healthcare directly.
Why Choose Steris Healthcare Pvt Ltd?
WHO-GMP certified manufacturing facilities
Trusted brand in neuro and pain management segments
Stringent quality control for consistent therapeutic efficacy
Affordable pricing with pan-India distribution
Backed by a team of experienced pharma professionals
Steris Healthcare stands out in the pharmaceutical industry due to its ethical practices, high-quality formulations, and commitment to patient care.
Frequently Asked Questions
1. What is gabapentin 300 mg used for?
Gabapentin 300 mg is used to treat neuropathic pain, partial seizures, and sometimes restless leg syndrome or fibromyalgia.
2. How long does it take for STARGAB 300 to work?
It may take a few days to weeks for full pain relief, though some patients notice improvement within the first few doses.
3. Can gabapentin 300 mg tablet be taken long-term?
Yes, under medical supervision, gabapentin can be used long-term for chronic pain or seizure disorders.
4. Are there any foods or drugs to avoid while using gabapentin 300 mg?
Avoid alcohol, antacids within 2 hours of dosing, and use caution with other CNS depressants.
5. Why choose Steris Healthcare Pvt Ltd for gabapentin 300 mg?
Steris Healthcare offers quality-assured, cost-effective, and clinically reliable products manufactured in certified facilities with nationwide availability.
Conclusion
STARGAB 300 (gabapentin 300 mg) from Steris Healthcare Pvt Ltd is a reliable, clinically proven medication for managing neuropathic pain and seizure disorders. With a strong safety profile, clinical backing, and manufacturing excellence, STARGAB 300 ensures effective relief and improved patient outcomes. For those seeking high-quality gabapentin 300 mg tablets, Steris Healthcare is the name to trust.
