Introduction
Type 2 diabetes mellitus is a chronic metabolic disorder that requires effective and sustained blood glucose control to prevent long-term complications. GLICLAGLAZE MET is a combination oral antidiabetic medication containing Gliclazide SR (60 mg) and Metformin SR (500 mg). This dual-action formulation is designed to improve glycemic control in adults with type 2 diabetes when diet, exercise, or single-drug therapy alone is insufficient. By combining two complementary mechanisms of action, GLICLAGLAZE MET helps regulate blood sugar levels throughout the day while reducing the risk of diabetes-related complications.
Uses
GLICLAGLAZE MET is primarily prescribed for:
Management of type 2 diabetes mellitus in adults
Patients with poor glycaemic control on monotherapy
Reducing fasting and post-prandial blood glucose levels
Improving insulin sensitivity and pancreatic insulin secretion
Prevention of long-term diabetic complications such as neuropathy, nephropathy, and cardiovascular disorders
This medicine is used as part of a comprehensive diabetes management plan that includes diet control, physical activity, and regular monitoring.
Benefits
GLICLAGLAZE MET offers multiple benefits due to its sustained-release formulation and synergistic drug combination:
Dual glucose control: Gliclazide stimulates insulin release, while metformin reduces glucose production and improves insulin sensitivity.
Sustained action: SR formulation ensures prolonged blood sugar control with reduced fluctuations.
Lower risk of hypoglycemia: Compared to older sulfonylureas, gliclazide has a favorable safety profile when taken as prescribed.
Weight neutrality: Metformin helps prevent weight gain often associated with diabetes treatment.
Improved HbA1c levels: Long-term use helps maintain stable glycemic parameters.
Better patient compliance: Once-daily or physician-directed dosing supports consistent therapy.
Dosage
The dosage of GLICLAGLAZE MET should always be individualized by a healthcare professional based on blood glucose levels and patient response.
Usually taken once daily with or after meals
Tablets should be swallowed whole and not crushed or chewed
Regular monitoring of blood sugar is advised
Dose adjustments may be required in elderly patients or those with renal impairment
Do not stop or change the dose without consulting your doctor
Adherence to prescribed dosage and lifestyle recommendations is essential for optimal results.
Side Effects
Most patients tolerate GLICLAGLAZE MET well; however, some may experience mild to moderate side effects, including:
Nausea or vomiting
Abdominal discomfort or diarrhoea
Dizziness or headache
Hypoglycemia (especially with irregular meals)
Metallic taste in mouth
Rare but serious side effects may include lactic acidosis or severe hypoglycemia. Immediate medical attention is required if unusual symptoms occur.
Precautions and Warnings
Not recommended for patients with type 1 diabetes or diabetic ketoacidosis
Use with caution in individuals with kidney, liver, or heart disease
Avoid excessive alcohol consumption during treatment
Regular monitoring of kidney function and blood glucose is advised
Pregnant or breastfeeding women should use only if prescribed by a doctor
Inform your healthcare provider about all other medications being taken
GLICLAGLAZE MET should always be used under medical supervision.
FAQs;
1. What is GLICLAGLAZE MET used for?
GLICLAGLAZE MET is used to treat type 2 diabetes mellitus by controlling blood sugar levels when diet and exercise alone are not enough.
2. How does GLICLAGLAZE MET work?
Gliclazide increases insulin secretion from the pancreas, while metformin reduces glucose production in the liver and improves insulin sensitivity.
3. Is GLICLAGLAZE MET safe for long-term use?
Yes, when taken as prescribed and monitored regularly, it is safe and effective for long-term diabetes management.
4. Can GLICLAGLAZE MET cause hypoglycemia?
Hypoglycemia may occur, especially if meals are skipped or alcohol is consumed. Following dietary advice helps reduce this risk.
5. When should GLICLAGLAZE MET be taken?
It is usually taken with or after meals, as advised by a doctor, to reduce gastrointestinal side effects.
6. Can elderly patients use GLICLAGLAZE MET?
Yes, but dosage adjustments and regular monitoring may be required, especially for kidney function.
7. Can GLICLAGLAZE MET cause weight gain?
Metformin helps maintain weight neutrality, and most patients do not experience significant weight gain.
8. Is GLICLAGLAZE MET suitable for type 1 diabetes?
No, it is indicated only for type 2 diabetes mellitus.
9. Can I stop taking GLICLAGLAZE MET once sugar levels improve?
No. Stopping medication without medical advice may worsen blood sugar control.
10. Where can I buy GLICLAGLAZE MET in India?
GLICLAGLAZE MET is available at licensed pharmacies and authorized online medical stores across India.
Conclusion
GLICLAGLAZE MET is an effective combination therapy for managing type 2 diabetes mellitus. With the sustained-release benefits of gliclazide and metformin, it provides stable blood glucose control, improves insulin action, and supports long-term metabolic health. When combined with lifestyle modifications and regular monitoring, GLICLAGLAZE MET helps patients achieve better glycemic outcomes and reduces the risk of diabetes-related complications, making it a reliable option in modern diabetes care.
