Introduction
NIMONIDIP 30 is a trusted pharmaceutical formulation from Steris Healthcare, containing Nimodipine 30mg as its active ingredient. Primarily known for its neuroprotective properties, tab nimodipine 30mg is widely prescribed in clinical practice for managing cerebral vasospasm and improving outcomes in subarachnoid hemorrhage patients. With proven efficacy and a strong safety profile, nimodipine 30mg tablet has earned its place in neurocritical care across the globe.
Chemical Composition and Formulation
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Active Ingredient: Nimodipine BP (30mg)
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Form: Oral tablet (tab nimodipine 30mg)
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Packaging: Blister pack of 10 or 30 tablets (varies by market)
Mechanism of Action
Nimodipine 30mg is a dihydropyridine calcium channel blocker that selectively targets cerebral blood vessels. By inhibiting the influx of calcium ions through L-type voltage-gated calcium channels, it prevents vascular smooth muscle contraction, resulting in cerebral vasodilation. This selective action on the brain vasculature helps reduce the risk of ischemic damage following aneurysmal subarachnoid hemorrhage.
Uses and Indications
Nimodipine 30mg tablet uses:
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Prevention and treatment of cerebral vasospasm following subarachnoid hemorrhage (SAH)
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Adjunct therapy in ischemic neurological deficits
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Investigational use in other neurovascular disorders
Tab nimodipine 30mg uses also include improving neurological recovery by enhancing cerebral perfusion.
Dosage and Administration
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Standard Adult Dose: 60 mg (two tab nimodipine 30mg) every 4 hours for 21 days
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Route: Oral
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Administer on an empty stomach for better absorption
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In cases of hypotension, dose adjustment may be required under medical supervision
Efficacy and Clinical Evidence
Clinical trials have consistently shown that nimodipine 30mg significantly reduces the incidence of poor neurological outcomes in patients with aneurysmal SAH. In landmark studies such as the British Aneurysm Nimodipine Trial, patients receiving tab nimodipine 30mg showed improved survival and neurological function.
Side Effects and Safety Profile
Most patients tolerate nimodipine 30mg well. However, possible side effects include:
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Hypotension
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Dizziness
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Flushing
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Nausea
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Bradycardia (rare)
These adverse effects are usually mild and dose-dependent.
Contraindications and Precautions
Contraindicated in:
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Severe hypotension
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Advanced hepatic impairment
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Hypersensitivity to nimodipine or any component of the formulation
Precautions:
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Monitor blood pressure regularly
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Use cautiously in patients with liver disease
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Avoid intravenous administration due to risk of fatal outcomes
Drug Interactions
Nimodipine 30mg interacts with:
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CYP3A4 inhibitors (e.g., ketoconazole, erythromycin): May increase nimodipine plasma levels
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CYP3A4 inducers (e.g., rifampin, phenytoin): May reduce therapeutic efficacy
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Antihypertensives: Additive hypotensive effects
Warnings and Regulatory Status
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Not for IV use
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Should be prescribed only under strict medical supervision
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Approved by major regulatory agencies (e.g., DCGI, EMA) for specific indications
Nimodipine 30mg tablet is a prescription-only medicine
Patient Advice and Tips
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Take tab nimodipine 30mg exactly as prescribed
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Do not crush or chew the tablets
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Inform your doctor about any other medications or supplements
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Avoid grapefruit juice while on treatment
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Store in a cool, dry place away from direct sunlight
Availability
NIMONIDIP 30is available in pharmacies and hospital supply chains across India and selected global markets. Distributed by Steris Healthcare, a company known for high-quality formulations and stringent manufacturing standards.
Frequently Asked Questions
Q1: What is nimodipine 30mg tablet used for?
A: It is used to prevent cerebral vasospasm and neurological deterioration after a subarachnoid hemorrhage.
Q2: Can I take tab nimodipine 30mg with food?
A: It is best taken on an empty stomach to enhance absorption.
Q3: Are there any major side effects of nimodipine 30mg?
A: Hypotension and dizziness are common; consult your doctor if symptoms persist.
Why Choose Steris Healthcare?
Steris Healthcare is a renowned name in the pharmaceutical industry, known for its focus on quality, efficacy, and safety. NIMONIDIP 30 reflects Steris Healthcare’s commitment to evidence-based medicine, affordability, and patient well-being. The product undergoes stringent quality control measures and complies with global regulatory standards.
Conclusion
NIMONIDIP 30, powered by nimodipine 30mg, is a clinically trusted solution in the management of cerebral vasospasm and neurological protection post-SAH. Its well-documented efficacy, coupled with Steris Healthcare’s reliability, makes it a preferred choice for healthcare professionals. When used appropriately, tab nimodipine 30mg can significantly improve patient outcomes and reduce neurological complications.
