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Prucalopride 1 mg : for Chronic Constipation Relie...

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Prucalopride 1 mg : for Chronic Constipation Relief

PRUCOLPRIDE 1 is an advanced gastrointestinal prokinetic medication containing Prucalopride 1 mg, developed specifically for the treatment of chronic idiopathic constipation (CIC) in adults. Unlike traditional laxatives that only relieve symptoms temporarily, PRUCOLPRIDE 1 addresses the underlying cause of constipation by directly stimulating colonic motility.

This innovative treatment is a selective 5-HT4 receptor agonist, offering a scientifically targeted approach to enhance bowel movements in patients for whom lifestyle changes and conventional laxatives have failed to provide adequate relief.

Key Features and Ingredients

  • Active Ingredient: Prucalopride 1 mg

  • Pharmacological Class: Selective serotonin (5-HT4) receptor agonist

  • Form: Oral tablet

  • Mechanism of Action: Stimulates 5-HT4 receptors in the enteric nervous system to enhance intestinal motility, particularly in the colon

  • Target Condition: Chronic idiopathic constipation (CIC)

Usage

PRUCOLPRIDE 1 is prescribed to adult patients, particularly women, who suffer from long-standing constipation not associated with any structural or metabolic condition. It is highly effective for individuals who have not responded to fiber supplements, stool softeners, or over-the-counter laxatives.

Dosage and Administration:

  • Recommended Dose: 1 mg once daily

  • Route: Oral, with or without food

  • Duration of Treatment: Can be used long-term under medical supervision

  • Special Populations: Dose adjustment may be required in elderly patients or those with severe renal impairment

Administration Tips:

  • Consistency is key: take the medication at the same time each day

  • Maintain hydration and a fiber-rich diet to support optimal gastrointestinal function during treatment

Benefits

  • Restores Natural Bowel Rhythm: PRUCOLPRIDE 1 promotes spontaneous complete bowel movements (SCBMs) without reliance on harsh laxatives.

  • Clinically Proven Efficacy: Studies demonstrate significant improvement in bowel movement frequency, stool consistency, and overall patient satisfaction.

  • Improves Quality of Life: Reduces abdominal discomfort, bloating, and straining, leading to better daily functioning and well-being.

  • Well-Tolerated: Most common side effects are mild, such as headache, nausea, or diarrhea, which usually resolve with continued use.

  • Non-Habit Forming: Unlike stimulant laxatives, PRUCOLPRIDE 1 does not cause dependency, making it suitable for long-term therapy.

  • Rapid Onset of Action: Some patients may notice improvement within the first week of treatment.

Key Advantages Over Traditional Treatments

  • Selective Targeting: Its action on 5-HT4 receptors means fewer systemic side effects and minimal cardiac risk, unlike older drugs in this class.

  • No Tachyphylaxis: Long-term use does not reduce effectiveness, which is common with some laxatives.

  • Enhanced Patient Compliance: Once-daily dosing and a favorable side effect profile encourage adherence.

Safety and Precautions

  • Contraindications: Not recommended in patients with intestinal perforation, obstruction, or severe inflammatory bowel conditions.

  • Use with Caution: In patients with renal impairment or a history of cardiovascular disease

  • Monitoring: While rare, any signs of severe abdominal pain or unusual side effects should be promptly reported to a healthcare provider

Conclusion

PRUCOLPRIDE 1, with Prucalopride 1 mg, offers a modern and effective solution to a problem that affects millions—chronic idiopathic constipation. By enhancing colonic motility at the neural level, it helps restore a more natural and comfortable bowel function, significantly improving patients' quality of life.

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options. The company offers a wide range of healthcare products, catering to various medical needs, from rare disease treatments to essential healthcare products. Sterispharma's product range includes solutions for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. Medicines can be conveniently ordered via Our websites—Sterisonline, Sterisindia, and Sterispharma.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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 2025-04-15T07:20:27