sacubitril and valsartan tablets 25 mg

Heart failure is a prevalent cardiovascular condition that can significantly impact a patient’s quality of life and longevity. Managing heart failure effectively requires medications that not only relieve symptoms but also improve heart function and reduce hospitalization risks. Sacubitril and Valsartan tablets, marketed as SACUSMART 25, provide an advanced therapeutic option for patients with heart failure, combining two potent ingredients that work together to optimize heart health. Manufactured by Steris Healthcare Pvt. Ltd., SACUSMART 25 is a safe, effective, and patient-friendly solution for long-term heart failure management.

Patients using SACUSMART 25 benefit from improved heart function, better symptom control, and enhanced quality of life, making it a cornerstone in modern heart failure therapy.

What is SACUSMART 25?

SACUSMART 25 is an oral tablet that contains:

• Sacubitril 12 mg – a neprilysin inhibitor

• Valsartan 13 mg – an angiotensin receptor blocker (ARB)

This combination is primarily used for heart failure with reduced ejection fraction (HFrEF). By targeting two important mechanisms involved in cardiovascular regulation, SACUSMART 25 helps reduce the heart’s workload, improve blood circulation, and lower the risk of complications associated with heart failure.

Key indications include:

• Treatment of heart failure

• Symptom relief such as shortness of breath, fatigue, and swelling

• Reduction in risk of hospitalization and cardiovascular mortality

Composition of SACUSMART 25

• Active Ingredients: Sacubitril 12 mg + Valsartan 13 mg (Total 25 mg)

• Dosage Form: Tablet

• Brand Name: SACUSMART 25

• Manufacturer: Steris Healthcare Pvt. Ltd.

Mechanism of Action

Sacubitril and Valsartan tablets provide a dual mechanism to manage heart failure effectively:

1. Sacubitril:

• Inhibits neprilysin, an enzyme responsible for breaking down natriuretic peptides.

• Natriuretic peptides improve blood vessel relaxation, reduce fluid retention, and lower cardiac stress.

2. Valsartan:

• Blocks angiotensin II receptors, preventing blood vessel constriction.

• Reduces blood pressure, prevents cardiac remodeling, and decreases strain on the heart.

The combination ensures comprehensive management of heart failure, addressing both fluid retention and high blood pressure, which are common complications in patients with reduced heart function.

Therapeutic Uses of SACUSMART 25

SACUSMART 25 is widely prescribed for:

• Heart Failure with Reduced Ejection Fraction (HFrEF): Enhances heart pumping efficiency.

• Reduction in Cardiovascular Mortality: Decreases the risk of death in heart failure patients.

• Symptom Management: Helps alleviate fatigue, breathlessness, and edema.

• Improved Quality of Life: Reduces hospitalization and supports daily activity levels.

This makes SACUSMART 25 a valuable medication for patients who require consistent and effective heart failure management.

Key Benefits of SACUSMART 25

• Dual Mechanism for Maximum Efficacy: Sacubitril and Valsartan work together to improve heart function and reduce cardiac stress.
  
  

• Reduces Hospitalization: Helps lower the frequency of hospital visits due to heart failure exacerbations.

• Enhances Survival: Proven to reduce mortality in patients with HFrEF.

• Symptom Relief: Controls fluid retention, fatigue, and shortness of breath.

• Patient-Friendly Formulation: Easy-to-take oral tablet ensures better adherence.

• Clinically Validated: Supported by scientific research and recommended in heart failure guidelines.

Dosage and Administration

• Recommended Dose: Usually one tablet twice daily, or as prescribed by a healthcare professional.

• Can be taken with or without food.

• Regular daily dosing is critical for optimal efficacy.

• Dose adjustments may be required for patients with kidney or liver impairment.

Important: Patients switching from ACE inhibitors must observe a 36-hour washout period before starting SACUSMART 25 to reduce the risk of angioedema.

Possible Side Effects

Most patients tolerate SACUSMART 25 well; however, some may experience:

• Dizziness or low blood pressure

• Elevated potassium levels (hyperkalemia)

• Kidney function changes

• Mild cough

• Rarely, angioedema (swelling of the face, lips, or throat)

Patients should seek immediate medical attention if they experience severe swelling, breathing difficulties, or other serious symptoms.

Precautions and Warnings

• Avoid use in patients with a history of angioedema, severe hypotension, or significant kidney impairment.

• Pregnancy: Should not be used during the second or third trimester.

• Regular monitoring of blood pressure, kidney function, and electrolytes is recommended.

• Do not combine with ACE inhibitors unless under strict medical supervision.

• Do not abruptly discontinue therapy without consulting your healthcare provider.

Storage Instructions

• Store tablets at room temperature (below 25°C).

• Protect from moisture, heat, and sunlight.

• Keep the medication in a tightly closed container.

• Store out of reach of children.

Why Choose Steris Healthcare Pvt. Ltd.?

Steris Healthcare Pvt. Ltd. is a trusted pharmaceutical company known for producing high-quality, effective, and safe medications. Their commitment to quality is reflected in:

• WHO-GMP Certified Manufacturing: Ensures consistent and reliable products.

• Clinically Proven Medications: All products undergo rigorous testing and validation.

• Patient-Centric Formulations: Designed for ease of use and improved adherence.

• Affordable and Dependable: Ensures access to advanced therapy without compromising quality.

• Healthcare Professional Recommended: Trusted globally for cardiovascular treatments.

Choosing SACUSMART 25 from Steris Healthcare ensures patients receive a dependable, effective solution for long-term heart failure management.

Patient Perspective: How SACUSMART 25 Improves Life

Heart failure can be debilitating, causing fatigue, breathlessness, and frequent hospitalizations. Patients often feel anxious about their condition and daily limitations.

SACUSMART 25 provides:

• Enhanced heart function and energy levels

• Symptom relief, including reduced swelling and breathlessness

• Lowered risk of hospitalization

• Improved overall quality of life and independence

With SACUSMART 25, patients can manage their heart failure more confidently and experience improved day-to-day well-being.

Frequently Asked Questions

Q1: What is SACUSMART 25 used for?
A: It is used to manage heart failure with reduced ejection fraction, improve symptoms, and reduce the risk of cardiovascular mortality.

Q2: How do Sacubitril and Valsartan work together?
A: Sacubitril enhances natriuretic peptides to relax blood vessels and reduce fluid retention, while Valsartan blocks angiotensin II receptors to lower blood pressure and reduce heart stress.

Q3: Can SACUSMART 25 be taken with food?
A: Yes, it can be taken with or without food.

Q4: What are the common side effects?
A: Mild dizziness, hypotension, elevated potassium levels, or cough. Serious side effects are rare.

Q5: Who should avoid this medication?
A: Patients with a history of angioedema, severe hypotension, kidney impairment, or pregnant women in the second and third trimesters.

Lifestyle Tips for Heart Failure Patients

In addition to taking SACUSMART 25, patients should adopt heart-healthy habits:

• Follow a low-salt, balanced die

• Engage in regular physical activity under medical supervision

• Avoid smoking and excessive alcohol

• Monitor daily weight to detect fluid retention early

• Manage stress and maintain a healthy weight

Combining lifestyle modifications with medication ensures optimal heart function and long-term cardiovascular health.

Conclusion

Sacubitril and Valsartan tablets offers a powerful and effective solution for patients with heart failure. Its dual-action mechanism improves heart function, reduces fluid retention, lowers hospitalization risk, and enhances survival, making it a clinically advanced choice for long-term heart failure management.

Backed by Steris Healthcare Pvt. Ltd., SACUSMART 25 ensures high-quality, safe, and reliable therapy. Patients seeking proven, effective, and convenient heart failure treatment can rely on SACUSMART 25 to improve quality of life and provide long-term cardiovascular protection.

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