TENELIGOLD PIO 20/15
Teneligliptin & Pioglitazone
TENELIGOLD PIO 20/15 is a combination medication used for the management of type 2 diabetes mellitus. It contains two active ingredients: Teneligliptin (20mg) and Pioglitazone (15mg). This combination helps improve blood sugar control by addressing different aspects of glucose metabolism in patients with type 2 diabetes. Composition Teneligliptin (20mg):
A dipeptidyl peptidase-4 (DPP-4) inhibitor that increases incretin hormones, stimulating insulin release and suppressing glucagon secretion to lower blood glucose levels.
Pioglitazone (15mg): A thiazolidinedione (TZD) that enhances insulin sensitivity in peripheral tissues such as muscle and adipose tissue, thereby improving insulin action and reducing insulin resistance.
Mechanism of Action
Teneligliptin: Inhibits the DPP-4 enzyme, increasing active incretin levels (GLP-1 and GIP), which enhance glucose-dependent insulin secretion and suppress glucagon release.
Pioglitazone: Activates peroxisome proliferator-activated receptor gamma (PPAR-γ), which regulates genes involved in glucose and lipid metabolism. This improves insulin sensitivity in peripheral tissues, leading to improved glycemic control.
Indications TENELIGOLD PIO 20/15 is indicated for:
Management of type 2 diabetes mellitus in adults.
Patients inadequately controlled on teneligliptin or pioglitazone monotherapy, or those already treated with both components separately.
Dosage and Administration
Recommended Dose: One tablet daily, with or without food.
Adjustment: Dosage adjustments may be necessary based on the patient\'s glycemic response and tolerability. Always follow the doctor\'s instructions.
Side Effects
Common side effects include:
Teneligliptin: Nasopharyngitis, upper respiratory tract infection, headache.
Pioglitazone: Edema, weight gain, upper respiratory tract infection, headache.
Precautions
Contraindications
Teneligliptin: Hypersensitivity to teneligliptin or any component of the formulation.
Conclusion
TENELIGOLD PIO 20/15 offers a combined approach to managing type 2 diabetes mellitus by targeting different mechanisms of glucose control. It combines the benefits of teneligliptin\'s incretin-based action with pioglitazone\'s insulin-sensitizing effects. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma\'s mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology.
For further information
Email: info@sterispharma.com / contact@sterispharma.com
Call/WhatsApp: 7877551268, 7849827488
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Composition Teneligliptin
DPP-4 enzyme
insulin action
lipid metabolism
healthcare industry
Administration Recommended Dose
glucagon release
insulin sensitivity
glucose-dependent insulin secretion
glucose control
glucagon secretion
A thiazolidinedione
Pioglitazone TENELIGOLD PIO
adipose tissue
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two active ingredients
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WHO guidelines
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Respiratory Issues
Action Teneligliptin
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type 2 diabetes mellitus
upper respiratory tract infection
Nasal Conditions
combined approach
peripheral tissues
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weight gain
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broad range
extensive demands
glucose metabolism
Precautions Contraindications
peroxisome proliferator-activated receptor gamma
rare conditions
glycemic response
blood sugar control
DPP-4) inhibitor
Common side effects
dipeptidyl peptidase-4
One tablet
insulin release
different aspects
Dosage adjustments
combination medication
active incretin levels
insulin-sensitizing effects