Nail fungus, medically known as onychomycosis, is a common yet stubborn fungal infection affecting fingernails and toenails. It often begins as a white or yellow discoloration and gradually progresses to nail thickening, brittleness, crumbling edges, and even pain in severe cases. Due to the slow growth of nails and deep fungal penetration, nail fungus is notoriously difficult to treat with topical medicines alone.
Oral antifungal therapy has emerged as the most effective solution for moderate to severe nail infections. Among these, the combination of Terbinafine and Itraconazole has shown superior outcomes. CONARIS T200, manufactured by Steris Healthcare Pvt. Ltd., contains Terbinafine 250 mg and Itraconazole 200 mg, offering a powerful, dual-action approach for complete fungal eradication.
Understanding Nail Fungus (Onychomycosis)
Nail fungus is caused by dermatophytes, yeasts, or non-dermatophyte molds that thrive in warm and moist environments. Factors increasing the risk include:
Excessive sweating
Wearing tight or non-breathable footwear
Diabetes or poor blood circulation
Weak immune system
Nail trauma
Prolonged exposure to moisture
Without proper treatment, nail fungus can spread to other nails and surrounding skin, causing long-term damage and cosmetic concerns.
Why Terbinafine and Itraconazole Are Effective for Nail Fungus
Role of Terbinafine
Terbinafine is a fungicidal agent that inhibits squalene epoxidase, an essential enzyme required for fungal cell membrane synthesis. This leads to fungal cell death. Terbinafine is particularly effective against dermatophytes, the most common cause of nail fungus.
Role of Itraconazole
Itraconazole works by inhibiting ergosterol synthesis, an important component of fungal cell membranes. It has a broader spectrum of action, making it effective against yeasts and non-dermatophyte molds.
Combination Advantage
Using Terbinafine and Itraconazole together, as in CONARIS T200, ensures:
Broader antifungal coverage
Faster fungal clearance
Reduced chances of resistance
Lower recurrence rates
This combination is especially beneficial in chronic, recurrent, or resistant nail fungal infections.
CONARIS T200: Advanced Therapy for Nail Fungus
CONARIS T200 by Steris Healthcare Pvt. Ltd. is a high-strength antifungal tablet containing:
Terbinafine 250 mg
Itraconazole 200 mg
This formulation is designed to penetrate deep into the nail bed, where fungi reside, ensuring complete eradication and healthy nail regrowth.
Uses of Terbinafine and Itraconazole in Nail Fungus
CONARIS T200 is primarily used for:
Fungal infections of fingernails and toenails
Chronic onychomycosis
Recurrent nail fungus not responding to single-drug therapy
Mixed fungal infections involving dermatophytes and yeasts
It may also be prescribed for associated skin fungal infections if present.
Benefits of Using CONARIS T200 for Nail Fungus
1. Deep Nail Penetration
Both drugs concentrate in the nail plate and nail bed, ensuring effective fungal elimination.
2. Broad-Spectrum Antifungal Action
Covers dermatophytes, yeasts, and molds responsible for nail infections.
3. Faster Clinical Improvement
Reduces discoloration, thickening, and brittleness more efficiently than monotherapy.
4. Lower Risk of Recurrence
Combination therapy ensures complete fungal eradication, minimizing relapse.
5. Suitable for Severe and Resistant Cases
Ideal for patients with long-standing or treatment-resistant nail fungus.
6. Trusted Quality from Steris Healthcare Pvt. Ltd.
Manufactured under strict quality standards for safety, efficacy, and consistency.
Dosage and Administration
Recommended Dose: One tablet of CONARIS T200 once daily, preferably after meals, or as directed by the physician.
Duration of Treatment:
Fingernail infections: Typically 6–8 weeks
Toenail infections: May require 12 weeks or longer
Treatment duration depends on nail growth rate and infection severity.
Important: Complete the full course even if symptoms improve early, as premature discontinuation may cause recurrence.
Side Effects of Terbinafine and Itraconazole
Most patients tolerate CONARIS T200 well. However, some may experience mild side effects such as:
Nausea or stomach discomfort
Headache
Diarrhea
Taste disturbance
Mild skin rash
Rare but Serious Side Effects
Liver enzyme elevation
Allergic reactions
Fatigue or loss of appetite
Regular monitoring may be advised during prolonged treatment.
Precautions and Warnings
Liver Disorders: Use with caution; liver function tests may be required.
Pregnancy and Breastfeeding: Not recommended unless prescribed by a doctor.
Drug Interactions: Inform your doctor about other medicines, especially statins, anticoagulants, or cardiac drugs.
Alcohol Consumption: Avoid alcohol to reduce liver strain.
Not for Self-Medication: Always use under medical supervision.
Tips to Prevent Nail Fungus Recurrence
Keep nails clean, dry, and trimmed
Wear breathable footwear
Avoid sharing nail clippers or footwear
Use antifungal powders if prone to sweating
Maintain good foot hygiene
Conclusion
Nail fungus is a persistent condition that requires a powerful and targeted treatment approach. The combination of Terbinafine and Itraconazole offers one of the most effective oral therapies for onychomycosis. CONARIS T200 by Steris Healthcare Pvt. Ltd., with its high-strength formulation of Terbinafine 250 mg and Itraconazole 200 mg, delivers broad-spectrum antifungal action, deep nail penetration, faster recovery, and reduced recurrence.
When used as prescribed, CONARIS T200 helps restore healthy nails, improves appearance, and enhances patient confidence, making it a reliable choice for managing nail fungal infections effectively.
