SACUSMART 50 is a prescription medication formulated with Sacubitril 50 mg and Valsartan 50 mg, designed to manage heart failure and improve cardiovascular health. This combination tablet belongs to a class of drugs known as angiotensin receptor-neprilysin inhibitors (ARNIs), which work by reducing strain on the heart, improving cardiac efficiency, and lowering blood pressure. Heart failure is a chronic condition in which the heart cannot pump blood effectively, leading to fatigue, shortness of breath, and fluid retention. SACUSMART 50 offers a scientifically advanced approach to supporting heart function, enhancing quality of life, and reducing hospitalization risk in patients with chronic heart failure. Uses SACUSMART 50 is primarily prescribed for: Heart Failure with Reduced Ejection Fraction (HFrEF): Helps improve heart function and symptoms in patients with chronic heart failure. Blood Pressure Control: Assists in lowering elevated blood pressure in patients with cardiovascular risk. Prevention of Heart Failure Complications: Reduces risk of hospitalization and progression of heart failure. Post-Myocardial Infarction Therapy (off-label): May be prescribed to support cardiac recovery under medical supervision. Benefits 1. Dual Mechanism for Heart Protection Sacubitril enhances natriuretic peptide activity, promoting vasodilation, sodium excretion, and reduced fluid overload. Valsartan blocks the angiotensin II receptor, preventing vasoconstriction and lowering blood pressure. Together, they provide superior heart protection. 2. Improves Heart Function By reducing cardiac workload and improving ventricular efficiency, SACUSMART 50 helps alleviate symptoms like shortness of breath, fatigue, and swelling. 3. Reduces Hospitalization Risk Clinical studies indicate that ARNIs like SACUSMART 50 significantly lower the risk of heart failure-related hospitalization compared to conventional therapies. 4. Supports Long-Term Cardiovascular Health Regular use under medical supervision helps prevent disease progression and improves overall quality of life for patients with heart failure. 5. Convenient Oral Tablet Easy-to-take tablets ensure better compliance and consistent dosing. Dosage Recommended Dose: Usually one tablet of SACUSMART 50 once or twice daily, depending on the patient’s condition and physician’s prescription. Administration: Take the tablet with or without food, at the same time each day. Swallow whole with water. Individualization: Dosage may be adjusted based on kidney function, blood pressure, and patient tolerance. Important: Never adjust or skip doses without consulting a doctor, as irregular intake may worsen heart failure symptoms. Side Effects SACUSMART 50 is generally well-tolerated. Mild side effects may include: Dizziness or lightheadedness Low blood pressure (hypotension) Fatigue or weakness Cough Stomach upset or nausea Serious Side Effects (Rare) Severe hypotension Kidney dysfunction Hyperkalemia (high potassium levels) Angioedema (swelling of face, lips, or throat) Seek immediate medical attention if severe side effects occur. Precautions and Warning Pregnancy and Breastfeeding: Not recommended; consult a physician for alternatives. Kidney or Liver Disorders: Dose adjustment and monitoring may be required. Electrolyte Monitoring: Regular checks for potassium and renal function are advised. Drug Interactions: Inform your doctor about other medications, especially ACE inhibitors, ARBs, potassium-sparing diuretics, or NSAIDs. Avoid Sudden Discontinuation: Stopping the medication abruptly can worsen heart failure. Lifestyle Measures: Maintain a low-sodium diet, exercise as advised, and monitor daily weight to detect fluid retention early. Conclusion SACUSMART 50, containing Sacubitril 50 mg and Valsartan 50 mg, is a clinically advanced therapy for managing heart failure with reduced ejection fraction and supporting cardiovascular health. By combining dual mechanisms—neprilysin inhibition and angiotensin receptor blockade—it effectively reduces cardiac workload, improves heart efficiency, and minimizes complications associated with chronic heart failure. When used under medical supervision, SACUSMART 50 enhances quality of life, reduces hospitalization risk, and supports long-term heart health, making it a trusted choice for patients seeking effective heart failure management.
| Active ingredient | Sacubitril and Valsartan Tablets 50 mg |
| Brand Name | SACUSMART |
| Manufactured By | Steris Healthcare Pvt Ltd |
| Package SIZE | 10x1x14 Tablets |
| Dosage | As Directed By The Physician |
| Storage | Store In A Cool & Dry Place |
| Country of origin | INDIA |