Dabigatran etexilate 110 mg
DABIGATREX 110 is a modern, highly effective oral anticoagulant used to prevent and treat blood clots. Its active ingredient, Dabigatran Etexilate 110 mg, belongs to a class of medications known as Direct Thrombin Inhibitors. Unlike traditional anticoagulants such as warfarin, Dabigatran offers predictable results without the need for frequent blood monitoring.
Primarily prescribed to prevent stroke and systemic embolism in patients with non-valvular atrial fibrillation (AF), DABIGATREX 110 also plays a key role in the treatment and prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE). With its rapid onset of action, fixed dosing, and low food or drug interactions, DABIGATREX 110 has transformed anticoagulant therapy.
Key Features and Ingredients
Composition:
Each capsule contains: Dabigatran Etexilate Mesylate equivalent to 110 mg Dabigatran Etexilate
Dosage form: Hard gelatin capsule
Drug class: Direct Oral Anticoagulant (DOAC) / Direct Thrombin Inhibitor
Key Features:
Rapid and reliable anticoagulant effect
No routine INR monitoring required
Fixed-dose oral therapy
Low risk of food-drug interactions
Proven efficacy in stroke prevention
Suitable for long-term use
Reversible with specific antidote (Idarucizumab) in case of emergency
Usage
DABIGATREX 110 is taken orally, usually twice daily, as directed by a physician. The capsules should be swallowed whole, not crushed or chewed, as this can increase the risk of bleeding.
Indications for Use:
Prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation
Treatment and prevention of recurrence of DVT and PE
Prophylaxis of venous thromboembolism after orthopedic surgeries (e.g., hip or knee replacement)
Dosage Recommendations:
110 mg twice daily in most patients
Dosage may be adjusted for elderly individuals, those with moderate renal impairment, or those at higher risk of bleeding
Important Considerations:
Maintain consistent dosing schedule
Avoid alcohol and NSAIDs, which may increase bleeding risk
Do not stop taking DABIGATREX 110 without medical advice, as doing so can increase the risk of blood clots
Benefits of DABIGATREX 110 (Dabigatran Etexilate 110 mg)
1. Stroke Prevention in Atrial Fibrillation
DABIGATREX 110 is highly effective in preventing ischemic stroke and embolism in patients with non-valvular atrial fibrillation, without the need for regular blood monitoring that is required with older anticoagulants like warfarin.
2. Effective in DVT and PE Treatment
The drug is indicated for the acute treatment and prevention of recurrent DVT and PE, providing reliable anticoagulation for patients after initial treatment with parenteral anticoagulants.
3. Superior Safety Profile
Compared to traditional anticoagulants, DABIGATREX 110 is associated with a lower risk of intracranial hemorrhage, making it a safer long-term therapy, especially for elderly patients.
4. Convenient Dosing
With fixed dosing and no need for routine coagulation monitoring, DABIGATREX 110 simplifies anticoagulation management for both patients and clinicians.
5. Fewer Food and Drug Interactions
Unlike warfarin, Dabigatran is not significantly affected by vitamin K intake, and it has minimal interaction with other commonly used drugs, allowing for greater dietary and medicinal flexibility.
6. Reversible in Emergency
In life-threatening bleeding situations or when emergency surgery is needed, Dabigatran’s effects can be reversed using Idarucizumab, a specific reversal agent, making it one of the safest options among DOACs.
Who Should Use DABIGATREX 110?
DABIGATREX 110 is especially beneficial for:
Patients with non-valvular atrial fibrillation at risk for stroke
Individuals recovering from DVT or PE
Those undergoing orthopedic surgeries with a risk of venous thromboembolism
Patients who cannot tolerate warfarin or require an anticoagulant without regular monitoring
However, it should be used cautiously or avoided in:
Severe renal impairment (CrCl <30 mL/min)
Active bleeding disorders
History of gastrointestinal bleeding
Pregnant or breastfeeding women, unless absolutely necessary
Possible Side Effects
Like all medications, DABIGATREX 110 may cause some side effects, most of which are related to its anticoagulant nature.
Common Side Effects:
Gastrointestinal discomfort
Indigestion
Nausea
Minor bleeding (gums, nosebleeds)
Serious Side Effects (Seek Immediate Medical Help):
Unusual bruising or bleeding
Blood in urine or stools
Severe headaches or dizziness
Signs of allergic reaction (rash, swelling, difficulty breathing)
Regular follow-up and monitoring of renal function are essential, especially in elderly patients.
Conclusion
DABIGATREX 110, containing Dabigatran Etexilate 110 mg, represents a modern advancement in oral anticoagulation therapy. With its fixed-dose regimen, rapid onset, and favorable safety profile, it provides a convenient, effective alternative to traditional anticoagulants. Its ability to prevent stroke, treat and prevent DVT/PE, and reduce the burden of monitoring makes it a preferred choice for many clinicians and patients alike.
Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options. The company offers a wide range of healthcare products, catering to various medical needs, from rare disease treatments to essential healthcare products. Sterispharma's product range includes solutions for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. Medicines can be conveniently ordered via Our websites—Sterisonline, Sterisindia, and Sterispharma.
For further information
Email: info@sterispharma.com / contact@sterispharma.com
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