Brand Name: GLIEMPAFLOZIN MET ER
Composition: Empagliflozin + Metformin Hydrochloride Extended Release
Manufacturer: Steris Healthcare Pvt. Ltd.
If you’re looking for a comprehensive and effective approach to managing Type 2 Diabetes Mellitus, Empagliflozin and Metformin Hydrochloride Extended Release tablets offer a dual-action treatment that is both scientifically proven and widely prescribed. Manufactured by Steris Healthcare, this combination medication helps control blood glucose levels while offering additional cardiovascular and renal benefits. This article explores the uses, benefits, price, dosage, side effects, and more about this potent anti-diabetic formulation.
What Are Empagliflozin and Metformin Hydrochloride Extended Release Tablets?
These tablets are a fixed-dose combination of Empagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, and Metformin Hydrochloride, a biguanide class antidiabetic agent. The extended-release formulation ensures a steady therapeutic effect throughout the day, reducing the frequency of dosing and improving patient compliance.
Together, this combination works in two ways:
Empagliflozin reduces glucose reabsorption in the kidneys, promoting its excretion via urine.
Metformin decreases hepatic glucose production and increases insulin sensitivity.
Empagliflozin and Metformin HCl ER Tablet Uses
Here are the primary indications for which this combination is commonly prescribed:
1. Type 2 Diabetes Mellitus
Helps control blood sugar levels in adults with Type 2 diabetes
Often used as an adjunct to diet and exercise
2. Cardiovascular Risk Reduction
Empagliflozin is known to reduce the risk of cardiovascular death in diabetic patients with established heart disease
3. Chronic Kidney Disease (CKD)
Offers renal protection and slows the progression of kidney damage in patients with Type 2 diabetes
How Do These Tablets Work?
Mechanism of Action:
Empagliflozin: Inhibits SGLT2 in the renal proximal tubules, reducing glucose reabsorption and increasing glucose excretion.
Metformin Hydrochloride (ER): Decreases hepatic glucose production, delays intestinal glucose absorption, and improves insulin sensitivity.
Together, they provide comprehensive glycemic control and reduce complications associated with diabetes.
Key Features of Empagliflozin + Metformin ER Tablets by Steris Healthcare
Extended-Release Formula: Once-daily dosing with controlled drug release
Cardio-Renal Benefits: Supports heart and kidney health in diabetic patients
Dual Mechanism: Targets multiple pathways of glucose regulation
GMP & WHO-Certified Manufacturing: Ensures global quality standards
Trusted Brand: Backed by Steris Healthcare’s reputation for clinical excellence
Benefits of Empagliflozin and Metformin HCl ER Tablets
Here’s how this powerful combination helps manage diabetes more effectively:
Better Glycemic Control
Improves both fasting and postprandial glucose levels.
Weight Reduction
Empagliflozin promotes weight loss due to calorie loss through urinary glucose excretion.
Cardiovascular Protection
Reduces risk of heart failure and cardiovascular-related death in patients with high CV risk.
Kidney Health Support
Delays progression of diabetic nephropathy and improves eGFR levels.
Reduced Risk of Hypoglycemia
Since it doesn’t stimulate insulin secretion, the chances of hypoglycemia are relatively lower compared to sulfonylureas.
Dosage and Administration
Recommended Dosage: As directed by your physician—commonly 1 tablet once or twice daily, depending on strength
Administration: Take with meals to reduce gastrointestinal side effects
Available Strengths: Varying strengths available (e.g., Empagliflozin 10 mg/25 mg + Metformin ER 500 mg/1000 mg)
Note: Always follow your healthcare provider’s prescription for the appropriate dosage and schedule.
Side Effects of Empagliflozin and Metformin ER Tablets
While this combination is generally well-tolerated, some individuals may experience side effects. These include:
Common Side Effects:
Nausea
Diarrhea
Headache
Increased urination
Genital fungal infections (more common in females)
Less Common but Serious Side Effects:
Lactic Acidosis (a rare but serious complication of Metformin)
Dehydration
Ketoacidosis (even with normal blood sugar)
Urinary tract infections
Hypotension (low blood pressure)
Seek immediate medical help if you experience symptoms like muscle pain, breathing difficulty, extreme fatigue, or dizziness.
Who Should Avoid This Medication?
Avoid using this medicine under the following conditions:
Severe Kidney Impairment (eGFR < 30 ml/min/1.73 m²)
Type 1 Diabetes MellitusHistory of Lactic Acidosis
Allergic Reaction to any component of the tablet
Pregnant or Breastfeeding Women (unless advised by a doctor)
Patients with Cardiovascular Instability or hypotension
Interactions with Other Drugs
Some drugs may interfere with the effectiveness or safety of this combination:
Diuretics
Insulin or insulin secretagogues
NSAIDs
ACE inhibitors/ARBs
Contrast agents (may affect kidney function with Metformin)
Storage Instructions
Store in a cool, dry place below 30°C
Protect from light and moisture
Keep out of reach of children
Empagliflozin and Metformin HCl Tablet Price in India
Pricesmay vary based on brand, packaging, and region. However, Steris Healthcare offers a cost-effective option with competitive pricing while maintaining top-notch quality.
You can check the latest price through Steris Healthcare Pvt Ltd or authorized distributors across India. Bulk or institutional purchase rates may also be available for hospitals and clinics.
Empagliflozin and Metformin ER Tablets
Steris Healthcare has emerged as a reliable and reputable manufacturer of high-quality pharmaceutical formulations, and its Empagliflozin and Metformin Hydrochloride Extended Release tablets are no exception. The brand ensures every tablet meets international quality benchmarks through WHO-GMP certified manufacturing processes and rigorous quality control measures.
What makes Steris Healthcare stand out is its commitment to patient-centric care, affordability, and product transparency. Whether you're a healthcare provider, patient, or pharmacy distributor, you can trust Steris Healthcare for consistent clinical outcomes, comprehensive documentation, and dependable supply chains.
With added cardiovascular and renal benefits packed in a patient-friendly extended-release formulation, these tablets are tailored for modern diabetes management. Steris Healthcare also offers timely cstomer support, fast delivery, and adherence to global regulatory norms, making it a preferred partner for diabetic care solutions.
