GLICLAGLAZE MR 30 is a prescription oral antidiabetic medicine containing gliclazide SR 30 mg as its active ingredient. It belongs to the sulfonylurea class of medications and is widely used for the management of Type 2 Diabetes Mellitus. The “MR” or “SR” stands for Modified Release / Sustained Release, which means the medicine is released slowly over time to provide steady blood sugar control throughout the day.
Gliclazide SR 30 mg works by stimulating the pancreas to release more insulin, thereby helping lower elevated blood glucose levels. Maintaining controlled blood sugar is crucial in preventing long-term diabetes complications such as nerve damage, kidney disease, vision problems, and cardiovascular disorders.
GLICLAGLAZE MR 30 is typically prescribed when diet, exercise, and lifestyle modifications alone are not sufficient to control blood sugar levels. It may be used alone or in combination with other antidiabetic medicines such as metformin or insulin, depending on the patient’s medical condition.
Uses
GLICLAGLAZE MR 30 Gliclazide SR 30 mg is primarily used for:
1. Type 2 Diabetes Mellitus
It helps control high blood sugar levels in adults diagnosed with Type 2 Diabetes, especially when the body does not produce enough insulin or when insulin is not used effectively.
2. Combination Therapy
Doctors may prescribe GLICLAGLAZE MR 30 along with:
Metformin
DPP-4 inhibitors
Insulin
Other oral antidiabetic drugs
to achieve better glycemic control.
3. Prevention of Diabetes Complications
By maintaining stable blood glucose levels, this medicine reduces the risk of:
Diabetic neuropathy (nerve damage)
Diabetic nephropathy (kidney damage)
Retinopathy (eye damage)
Cardiovascular diseases
Benefits
GLICLAGLAZE MR 30 offers multiple therapeutic advantages:
1. Effective Blood Sugar Control
The sustained-release formula ensures gradual release of gliclazide throughout the day, reducing sudden spikes in blood sugar levels.
2. Once-Daily Convenience
Due to its modified-release property, it is usually taken once daily, improving patient compliance.
3. Lower Risk of Hypoglycemia (Compared to Older Sulfonylureas)
Gliclazide is considered to have a relatively lower risk of causing severe low blood sugar episodes compared to some older sulfonylurea drugs when taken correctly.
4. Protective Effect on Blood Vessels
Studies suggest gliclazide may have antioxidant properties, which can help protect blood vessels from damage caused by prolonged high blood sugar.
5. Supports Long-Term Diabetes Management
Consistent use along with diet and exercise supports better HbA1c control and overall diabetes management.
Dosage
Recommended Dose
The typical starting dose of GLICLAGLAZE MR 30 (Gliclazide SR 30 mg) is:
30 mg once daily, usually taken with breakfast.
The doctor may adjust the dose depending on:
Blood sugar levels
HbA1c results
Individual response
Other medications being taken
Maximum Dose
The dose may be gradually increased under medical supervision if needed. Always follow your doctor’s prescription strictly.
How to Take
Swallow the tablet whole with water.
Do not crush, chew, or break the tablet.
Take it at the same time each day.
Always take it with food to reduce the risk of hypoglycemia.
Missed Dose
If you miss a dose:
Take it as soon as you remember (if it’s the same day).
Skip it if it’s almost time for the next dose.
Do not double the dose.
Side Effects
Like all medications, GLICLAGLAZE MR 30 may cause side effects, although not everyone experiences them.
Common Side Effects
Hypoglycemia (low blood sugar)
Headache
Dizziness
Nausea
Stomach discomfort
Symptoms of Low Blood Sugar
Sweating
Shaking
Hunger
Fast heartbeat
Confusion
If you experience hypoglycemia, consume a fast-acting carbohydrate such as glucose tablets, fruit juice, or sugar.
Rare but Serious Side Effects
Severe allergic reactions
Liver function abnormalities
Blood disorders
Seek immediate medical attention if you notice severe symptoms such as yellowing of the skin (jaundice), unusual bruising, or persistent weakness.
Precautions and Warning
Before taking GLICLAGLAZE MR 30, inform your doctor if you have:
1. Type 1 Diabetes
This medicine is not suitable for patients with Type 1 Diabetes.
2. Severe Kidney or Liver Disease
Dose adjustments may be required in patients with impaired kidney or liver function.
3. History of Hypoglycemia
If you frequently experience low blood sugar episodes, careful monitoring is required.
4. Pregnancy and Breastfeeding
Consult your doctor before use. Insulin is generally preferred during pregnancy.
5. Alcohol Consumption
Alcohol can increase the risk of hypoglycemia and should be consumed cautiously or avoided.
6. Elderly Patients
Older adults may be more sensitive to the effects of gliclazide and require careful dose monitoring.
Drug Interactions
Inform your healthcare provider about all medications you are taking, especially:
Other antidiabetic drugs
Blood pressure medications
Antifungal drugs
Antibiotics
Regular blood glucose monitoring is essential while taking this medication.
Conclusion
GLICLAGLAZE MR 30, containing gliclazide SR 30 mg, is an effective and reliable oral antidiabetic medication designed for long-term management of Type 2 Diabetes Mellitus. Its modified-release formulation ensures consistent blood sugar control with the convenience of once-daily dosing.
By helping stimulate insulin release and maintain stable glucose levels, GLICLAGLAZE MR 30 plays a vital role in reducing the risk of serious diabetes-related complications. When combined with a balanced diet, regular exercise, and proper medical supervision, it supports overall metabolic health and improved quality of life.
